Acute colonic pseudo-obstruction is managed with bolus neostigmine as shown in a recent prospective, double blind, placebo-controlled study. Parasympathetic stimulation with neostigmine leads to abdominal pain, salivation, and symptomatic bradycardia. We submit a more effective method may involve use of neostigmine infusion to reduce complications and improve efficacy.
Ogilvie H. Large intestine colic due to sympathetic deprivation: a new clinical syndrome. BMJ 1948;2:671-3.
Ponec RJ, Saunders MD, Kimmey MB. Neostigmine for treatment of acute colonic pseudo-obstruction. NEJM 1999;341:137-41.
Nanni G, Garini A, Luchetti P, Nanni G, Ronconi P, Castagneto M. Ogilvie′s syndrome (acute colonic pseudo-obstruction): review of the literature (Oct 1948 to Mar 1980) and report of four additional cases. Distal Colon Rectum 1982;25:157-66.
Penney DJ, Hillman K. Ogilvie′s syndrome: novel use of a continous neostigmine infusion. Clinical Intensive Care 2001;12:237-9.
Rutkow IM. Movements in surgical history. John Benjamin Murphy, 1857-1916. Arch Surg 2001;136:359.
Wendt E. Ueber den einfluss des intraabdominal druckes auf die absonderungsgesch windigkeit des harnes. Arch fur physiol heilkd 1867;527-75.
Pusajo J, Bumaschny E, Agurrola A. Post-operative intra abdominal pressure: its relation to splanchnic perfusion, sepsis, multi organ failure and surgical intervention. Int Critical Care Digest 1994;13:2-7.
Sugrue M, Jones F, Janjua KJ, Deane SA, Bristow P, Hillman K. Intra abdominal hypertension is an independent cause of post operative renal impairment. Arch Surg 1998;134:1082-5.
Citerio G, Vascotto E, Villa F, Celotti S, Pesenti A. Induced abdominal compartment syndrome increases pressure in neurotrauma patients. Crit Care Med 2001;29:1466-71.
Johnson CD, Rice RP, Kelvin FM, Williford ME. The radiographic evaluation of gross caecal distension: emphasis on caecal ileus. Am J Roentgenol 1985;145:1211-7.
Vantrappen G. Acute colonic pseudo-obstruction. Lancet 1993;341:152-3.