Indian Journal of Critical Care Medicine

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VOLUME 23 , ISSUE 10 ( October, 2019 ) > List of Articles

CASE REPORT

Trientine-induced Rhabdomyolysis in an Adolescent with Wilson's Disease

Sibel Yavuz, Gokhan Tumgor, Aysun Karabay Bayazıt

Keywords : Continued renal replacement therapy, Rhabdomyolysis, Trientine

Citation Information : Yavuz S, Tumgor G, Bayazıt AK. Trientine-induced Rhabdomyolysis in an Adolescent with Wilson's Disease. Indian J Crit Care Med 2019; 23 (10):489-490.

DOI: 10.5005/jp-journals-10071-23271

License: CC BY-NC 4.0

Published Online: 01-04-2019

Copyright Statement:  Copyright © 2019; The Author(s).


Abstract

Background: Drugs are very important in the etiology of nontraumatic rhabdomyolysis. Case descriptions: A 16-year-old male patient with Wilson's disease was admitted for myoclonic contractions. Oral trientine was started for neurological problems and tremor on the hands due to D-penicillamine 1 month ago. Patient was oligoanuric, and his creatine kinase level was 15197 U/L. Rhabdomyolysis was associated with trientine, and trientine treatment was stopped. Hemodiafiltration was performed. The patient began to urinate on the 24th day. Conclusion: This is the first pediatric patient with rhabdomyolysis induced by trientine. Drugs used should be questioned carefully in patients with rhabdomyolysis.


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  1. Vanholder R, Sever MS, Erek E, Lameire N. J Am Soc Nephrol 2000;11:1553–1561.
  2. Ward MM. Factors predictive of acute renal failure in rabdomyolisis. Arch İntern Med 1998;148:1553–1557.
  3. Melli G, Chaudhry V, Cornblath DR. Rhabdomyolysis: an evaluation of 475 hospitalized patients. Medicine (Baltimore) 2005;84:377–385.
  4. Epstein O, Sherlock S. Triethylene tetramine dihydrochloride toxicity in primary biliary cirrhosis. Gastroenterology 1980;78(6):1442–1445.
  5. Lu J. Triethylenetetramine pharmacology and its clinical applications. Mol Cancer Ther 2010;9:2458–2467.
  6. Dalvi A, Padmanaban M. Wilson's disease: Etiology, diagnosis, and treatment. Dis Mon 2014;60:450–459.
  7. European Association for Study of Liver. EASL Clinical Practice Guidelines: Wilson's disease. J Hepatol 2012;56:671–685.
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