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VOLUME 23 , ISSUE 12 ( December, 2019 ) > List of Articles

Original Article

Outcome of Noninvasive Ventilation in Acute Respiratory Failure

Sonal Arsude, Anil Sontakke, Ankita Jire

Keywords : Acute respiratory failure, Noninvasive ventilation, Outcome, Predictors

Citation Information : Arsude S, Sontakke A, Jire A. Outcome of Noninvasive Ventilation in Acute Respiratory Failure. Indian J Crit Care Med 2019; 23 (12):556-561.

DOI: 10.5005/jp-journals-10071-23291

License: CC BY-NC 4.0

Published Online: 01-08-2014

Copyright Statement:  Copyright © 2019; The Author(s).


Abstract

Background: Noninvasive ventilation (NIV) represents the delivery of positive pressure to the lungs without inserting an endotracheal tube. Noninvasive ventilation has been successfully used in patients with acute respiratory failure. There is a tremendous increase in usage of NIV in clinical settings aiming to reduce complications due to invasive ventilation and to improve resource utilization. It is imperative to watch for outcome of NIV in patients with acute respiratory failure. Materials and methods: A total of 50 patients were included in this prospective longitudinal study and divided into two groups: type I and type II respiratory failure. All patients were administered bilevel positive airway pressure (BIPAP) ventilator support system using full-face mask or nasal mask depending on the status of the patient. Dyspnea quantitated by modified Borg dyspnea score, heart rate (HR), respiratory rate (RR), blood pressure, and arterial blood gas analysis were assessed at the end of 4, 12, and 24 hours. Results: Respiratory rate and HR were significantly improved at the end of 4, 12, and 24 hours with NIPPV compared with baseline (0 hour) in both groups (p < 0.01). Statistically significant improvements in pH and PaO2 was seen with NIPPV at the end of 12 hours and 24 hours (p < 0.001) compared with the baseline in both type I and type II respiratory failure patients. Dryness of mouth and nose was noted in 3 (6.81%) patients with NIPPV. Conclusion: Study indicates that a trial of BIPAP is effective in improving gas exchange, reducing intubation, and length of stay in hospital in patients with acute respiratory failure.


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  1. Cabrini L, Landoni G, Oriani A, Plumari VP, Nobile L, Greco M, et al. Noninvasive ventilation and survival in acute care settings: a comprehensive systematic review and metaanalysis of randomized controlled trials. Crit Care Med 2015;43(4):880–888. DOI: 10.1097/CCM.0000000000000819.
  2. Lin C, Yu H, Fan H, Li Z. The efficacy of noninvasive ventilation in managing postextubation respiratory failure: a meta-analysis. Hear Lung 2014;43(2):99–104. DOI: 10.1016/j.hrtlng.2014.01.002.
  3. Kramer N, Meyer T, Meharg J, Cece R, Hill N. Randomized, prospective trial of noninvasive positive pressure ventilation in acute respiratory failure. Am J Respir Crit Care Med 1995;151(6):1799–1806. DOI: 10.1164/ajrccm.151.6.7767523.
  4. British Thoracic Society Standards of Care Committee. Non-invasive ventilation in acute respiratory failure. Thorax 2002;57(3):192–211. DOI: 10.1136/thorax.57.3.192.
  5. Budweiser S, Jörres R, Pfeifer M. Treatment of respiratory failure in COPD. Int J Chron Obstruct Pulmon Dis 2008;3(4):605–618. DOI: 10.2147/COPD.S3814.
  6. Grippi MA. Respiratory failure: an overview. Fishman's Pulmonary Diseases and Disorders, 5th ed., vol. 2 2017. pp. 2152–2161.
  7. George I, John G, John P, Peter JV, Christopher S. An evaluation of role of noninvasive positive pressure ventilation in the management of acute respiratory failure in a developing country. Indian J Med Sci 2007;61(9):495–504. DOI: 10.4103/0019-5359.34518.
  8. Lin M, Guo H, Huang M, Chen C, Wu C. Predictors of successful noninvasive ventilation treatment for patients suffering acute respiratory failure. J Chin Med Assoc 2008;71(8):392–398. DOI: 10.1016/S1726-4901(08)70089-3.
  9. Conti V, Paone G, Mollica C, Sebastiani A, Mannocci A, La Torre G, et al. Predictors of outcome for patients with severe respiratory failure requiring non invasive mechanical ventilation. Eur Rev Med Pharmacol Sci 2015;19(20):3855–3860.
  10. Ventrella F, Giancola A, Cappello S, Pipino M, Minafra G, Carbone M, et al. Use and performance of non-invasive ventilation in Internal Medicine Ward: a real-life study. Ital J Med 2015;9(3): 260–267.
  11. Brochard L, Mancebo J, Wysocki M, Lofaso F, Conti G. Noninvasive ventilation for acute exacerbation of chronic obstructive pulmonary disease. N Engl J Med 1995;333(13):817–822. DOI: 10.1056/NEJM199509283331301.
  12. Agarwal R, Handa A, Aggarwal AN, Gupta D, Behera D. Outcomes of noninvasive ventilation in acute hypoxemic respiratory failure in a respiratory intensive care unit in north India. Respir Care 2009;54(12):1679–1687.
  13. McLaughlin K, Murray I, Thain G, Currie G. Ward-based non-invasive ventilation for hypercapnic exacerbations of COPD: a “real-life” perspective. QJM 2010;103(7):505–510. DOI: 10.1093/qjmed/hcq063.
  14. Ibrahim B, Jaber D. The effectiveness of non-invasive ventilation in management of respiratory failure in palestine a prospective observational study. Egypt J Crit Care Med 2014;2(1):29–36. DOI: 10.1016/j.ejccm.2014.07.002.
  15. Antonelli M, Conti G, Moro M, Esquinas A, Gonzalez-Diaz G, Confalonieri M, et al. Predictors of failure of noninvasive positive pressure ventilation in patients with acute hypoxemic respiratory failure: a multi-center study. Intensive Care Med 2001;27(11): 1718–1728. DOI: 10.1007/s00134-001-1114-4.
  16. Bhattacharyya D, Prasad SM, Tampi PS, Ramprasad R. Early predictors of success of non-invasive positive pressure ventilation in hypercapnic respiratory failure. Med J Armed Forces India 2011;67(4):315–319. DOI: 10.1016/S0377-1237(11)60075-0.
  17. Pacilli A, Valentini I, Carbonara P, Marchetti A, Nava S. Determinants of noninvasive ventilation outcomes during an episode of acute hypercapnic respiratory failure in chronic obstructive pulmonary disease: the effects of comorbidities and causes of respiratory failure. Biomed Res Int 2014;2014:976783. DOI: 10.1155/2014/976783.
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