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VOLUME 26 , ISSUE 2 ( February, 2022 ) > List of Articles

CASE REPORT

Corona, Acute Ischemic Stroke, Malignant Cerebral Edema, and Hemo-adsorption: A Case Report

Mehul Shah, Zakaria Kaidawala, Arun Shah, Rushi Desphande

Keywords : Acute ischemic stroke, Corona, COVID-19, Cytosorb, Hemoadsorption, Hemoperfusion, Malignant cerebral edema

Citation Information : Shah M, Kaidawala Z, Shah A, Desphande R. Corona, Acute Ischemic Stroke, Malignant Cerebral Edema, and Hemo-adsorption: A Case Report. Indian J Crit Care Med 2022; 26 (2):235-238.

DOI: 10.5005/jp-journals-10071-24116

License: CC BY-NC 4.0

Published Online: 09-02-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Abstract

Background: COVID-19 infection can be associated with systemic hyperinflammation, hypercoagulable state, vasculitis, and cardiomyopathy leading to multiorgan failure. Use of extracorporeal blood purification has been shown to mitigate the cytokine storm, improving hemodynamic stability and pulmonary function. Case summary: We report a case of a young patient with malignant cerebral edema due to acute cerebrovascular accident, with COVID-19. He was taken up for life-saving decompression craniotomy amidst the cytokine storm and multiorgan failure, and was treated with steroids, antibiotics, and Cytosorb® therapy for the cytokine storm. IL-6 and PCT levels were reduced by 99.5 and 98.6%, respectively. Vasopressors were stopped on day 4 and successfully weaned off ventilator support by 2 weeks of tracheostomy. He was de-cannulated and discharged neurologically stable on day 32. Conclusion: Timely detection of COVID-19 and anti-inflammatory and hemo-adsorption measures may be helpful in modulating cytokine storm, thereby reducing morbidity and mortality.


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