Severe adult-onset still\'s disease mimicking systemic infection

Rajani Gubbala; Ganshyam Jagathkar; Nagalakshmikanth Reddy Mayaluri; K.P. Raghavendra

doi:10.4103/ijccm.IJCCM_208_18

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Severe adult-onset still\'s disease mimicking systemic infection

Rajani Gubbala, Ganshyam Jagathkar, Nagalakshmikanth Reddy Mayaluri, K.P. Raghavendra

Keywords : Adult-onset Still\'s disease, fever, procalcitonin

Citation Information : Gubbala R, Jagathkar G, Mayaluri NR, Raghavendra K. Severe adult-onset still\'s disease mimicking systemic infection. Indian J Crit Care Med 2018; 22 (8):616-618.

DOI: 10.4103/ijccm.IJCCM_208_18

License: CC BY-ND 3.0

Published Online: 01-08-2018

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Abstract

Adult-onset Still\'s disease (AOSD) is an uncommon entity that can mimic infection. Patients present with fever for more than 1-week, joint pain, and rash. We report a case of 22-year-old male who presented with fever, sore throat, and abdominal pain. During hospitalization, he had multiple episodes of tachycardia and tachypnea requiring mechanical ventilation. The patient had elevated white blood cell count, procalcitonin, and troponin. He was extensively investigated and diagnosed as AOSD. He responded to steroids and was discharged on day 20.

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Mert A, Ozaras R, Tabak F, Bilir M, Ozturk R, Ozdogan H, et al. Fever of unknown origin: A review of 20 patients with adult-onset still's disease. Clin Rheumatol 2003;22:89-93.
Yamaguchi M, Ohta A, Tsunematsu T, Kasukawa R, Mizushima Y, Kashiwagi H, et al. Preliminary criteria for classification of adult still's disease. J Rheumatol 1992;19:424-30.
Fautrel B, Le Moël G, Saint-Marcoux B, Taupin P, Vignes S, Rozenberg S, et al. Diagnostic value of ferritin and glycosylated ferritin in adult onset still's disease. J Rheumatol 2001;28:322-9.
Scirè CA, Cavagna L, Perotti C, Bruschi E, Caporali R, Montecucco C, et al. Diagnostic value of procalcitonin measurement in febrile patients with systemic autoimmune diseases. Clin Exp Rheumatol 2006;24:123-8.
Efthimiou P, Paik PK, Bielory L. Diagnosis and management of adult onset still's disease. Ann Rheum Dis 2006;65:564-72.
Santos Castañeda, Ricardo Blanco, Miguel A. González-Gay. Adult-onset Still's disease: Advances in the treatment. Best practice and research clinical rheumatology 2016;30;222-38.

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