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VOLUME 22 , ISSUE 10 ( 2018 ) > List of Articles


Anti-voltage-gated potassium channel antibody syndrome: A rare cause of hyponatremia in intensive care unit

Shashi Prakash

Keywords : Anti-voltage-gated potassium channel antibody syndrome, hypokalemia, hyponatremia, seizure, syndrome of inappropriate antidiuretic hormone secretion

Citation Information : Prakash S. Anti-voltage-gated potassium channel antibody syndrome: A rare cause of hyponatremia in intensive care unit. Indian J Crit Care Med 2018; 22 (10):746-748.

DOI: 10.4103/ijccm.IJCCM_480_17

License: CC BY-ND 3.0

Published Online: 01-06-2018

Copyright Statement:  Copyright © 2018; The Author(s).


Hyponatremia causing seizure is a common cause for admission in the critical care unit. Here, we describe a peculiar case of seizure due to hyponatremia, associated with anti-voltage-gated potassium channel antibody syndrome. This case emphasizes that how a proper workup can unveil unusual but potentially treatable causes of hyponatremia. The hallmark of this syndrome is that neurological symptoms may relapse or progress if the disorder is not recognized in time. This case report emphasizes the point that how a keen observation may decode subtle signs of the grave but potentially treatable pathologies.

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