Indian Journal of Critical Care Medicine

Register      Login



Volume / Issue

Online First

Related articles

VOLUME 22 , ISSUE 11 ( 2018 ) > List of Articles


Fatal iron toxicity in an adult: Clinical profile and review

Mandar Sane, Kamal Malukani, Rashmi Kulkarni, Abhishek Varun

Keywords : Ferrous sulfate, hepatic failure, Perl's stain, toxidrome

Citation Information : Sane M, Malukani K, Kulkarni R, Varun A. Fatal iron toxicity in an adult: Clinical profile and review. Indian J Crit Care Med 2018; 22 (11):801-803.

DOI: 10.4103/ijccm.IJCCM_188_18

License: CC BY-ND 3.0

Published Online: 01-12-2017

Copyright Statement:  Copyright © 2018; The Author(s).


Acute iron toxicity is usually seen in children with accidental ingestion of iron-containing syrups. However, the literature on acute iron toxicity with suicidal intent in adults is scant. We report an instance wherein an adult committed suicide by ingestion of multiple iron tablets. Delay in treatment was there due to misdiagnosis of the intoxicating agent. She developed fulminant hepatic failure with rapid clinical deterioration. Despite aggressive supportive management, the patient succumbed to the toxic doses of iron. Clinical course and postmortem features are discussed with a review of the literature.

PDF Share
  1. Abhilash KP, Arul JJ, Bala D. Fatal overdose of iron tablets in adults. Indian J Crit Care Med 2013;17:311-3.
  2. Baranwal AK, Singhi SC. Acute iron poisoning: Management guidelines. Indian Pediatr 2003;40:534-40.
  3. Singhi SC, Baranwal AK, M J. Acute iron poisoning: Clinical picture, intensive care needs and outcome. Indian Pediatr 2003;40:1177-82.
  4. Pestaner JP, Ishak KG, Mullick FG, Centeno JA. Ferrous sulfate toxicity: A review of autopsy findings. Biol Trace Elem Res 1999;69:191-8.
  5. Mahesh K, Rani R. A case of iron poisoning- case report. Int J Basic Appl Med Sci 2014;4:101-3.
  6. Geraci MJ, Heagney H. Iron overdose during pregnancy: Case and treatment review. Int J Clin Med 2012;3:715-21.
  7. Pillay VV. Modern Medical Toxicology. 4th ed. New Delhi: Jaypee Brothers Medical Publishers; 2013. p. 97.
  8. Mishra PK, Kulkarni R, Sane MR, Deshpande A, Kushwah M. Prospects of poisoning – A multi facet study. Arch Med Sadowej Kryminol 2016;66:235-43.
  9. Skoczynska A, Kwiecinska D, Kielbinski M, Lukaszewski M. Acute iron poisoning in adult female. Hum Exp Toxicol 2007;26:663-6.
  10. Tenenbein M. Toxicokinetics and toxicodynamics of iron poisoning. Toxicol Lett 1998;102-103:653-6.
  11. Robertson A, Tenenbein M. Hepatotoxicity in acute iron poisoning. Hum Exp Toxicol 2005;24:559-62.
  12. Dettmeyer RB. Forensic Histopathology Fundamentals and Perspectives. Berlin: Springer; 2011. p. 141.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.