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VOLUME 20 , ISSUE 10 ( 2016 ) > List of Articles

CASE REPORT

Successful engraftment after hematopoietic stem cell transplantation with infusion of donor stem cells through the extracorporeal membrane oxygenation circuit

Pilar Anton-Martin, Cindy Darnell-Bowens, Victor Aquino, Teresa Jones, Lakshmi Raman

Keywords : Engraftment, extracorporeal membrane oxygenation, hematopoietic stem cell transplantation, Wiskott-Aldrich syndrome

Citation Information : Anton-Martin P, Darnell-Bowens C, Aquino V, Jones T, Raman L. Successful engraftment after hematopoietic stem cell transplantation with infusion of donor stem cells through the extracorporeal membrane oxygenation circuit. Indian J Crit Care Med 2016; 20 (10):617-619.

DOI: 10.4103/0972-5229.192062

License: CC BY-ND 3.0

Published Online: 01-09-2017

Copyright Statement:  Copyright © 2016; The Author(s).


Abstract

Wiskott-Aldrich syndrome (WAS) is a rare X-linked primary immunodeficiency due to mutations in the WAS gene expressed in hematopoietic cells. Hematopoietic stem cell transplantation (HSCT) is the treatment of choice when an appropriate human leukocyte antigen-matched donor is available. The use of the extracorporeal membrane oxygenation (ECMO) circuit to infuse donor cells for HSCT has not been previously published in the literature. We describe a case of a child who had successful engraftment after HSCT with infusion of the donor stem cells through the ECMO circuit.


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