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VOLUME 21 , ISSUE 4 ( 2017 ) > List of Articles


Thrombotic thrombocytopenic purpura in a case of dengue fever: A rare presentation

Abhijit S. Gavali, Sandip Bartakke

Keywords : ADAMTS13, dengue fever, plasma exchange therapy, rare case presentation, thrombotic thrombocytopenic purpura

Citation Information : Gavali AS, Bartakke S. Thrombotic thrombocytopenic purpura in a case of dengue fever: A rare presentation. Indian J Crit Care Med 2017; 21 (4):226-228.

DOI: 10.4103/ijccm.IJCCM_27_16

License: CC BY-ND 3.0

Published Online: 01-04-2018

Copyright Statement:  Copyright © 2017; The Author(s).


Here, we present an unusual occurrence of thrombotic thrombocytopenic purpura (TTP) in a case of dengue fever. Both the conditions are fatal and can result in significant mortality and morbidity if left untreated. In this case, as soon as, we diagnosed the patient as having TTP, we treated her with plasma exchange therapy, steroids, and monoclonal antibodies such as rituximab. The patient responded very well to the treatment and completely recovered from neurological symptoms and laboratory parameters also normalized. Hence, timely diagnosis and starting appropriate treatment immediately are key factors for successful outcome.

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