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VOLUME 19 , ISSUE 1 ( 2015 ) > List of Articles


Permissive hypercapnia: Is there any upper limit?

Snehamayee Nayak

Citation Information : Nayak S. Permissive hypercapnia: Is there any upper limit?. Indian J Crit Care Med 2015; 19 (1):56-57.

DOI: 10.4103/0972-5229.148655

License: CC BY-ND 3.0

Published Online: 01-12-2015

Copyright Statement:  Copyright © 2015; The Author(s).


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  1. Garg SK. Permissive hypercapnia: Is there any upper limit? Indian J Crit Care Med 2014;18:612-4.
  2. Caples SM, Rasmussen DL, Lee WY, Wolfert MZ, Hubmayr RD. Impact of buffering hypercapnic acidosis on cell wounding in ventilator-injured rat lungs. Am J Physiol Lung Cell Mol Physiol 2009;296:L140-4.
  3. Joyce RR, McGee WT. Hypercapnic cerebral edema presenting in a woman with asthma: A case report. J Med Case Rep 2011;5:192.
  4. Stengl M, Ledvinova L, Chvojka J, Benes J, Jarkovska D, Holas J, et al. Effects of clinically relevant acute hypercapnic and metabolic acidosis on the cardiovascular system: An experimental porcine study. Crit Care 2013;17:R303.
  5. Weber T, Tschernich H, Sitzwohl C, Ullrich R, Germann P, Zimpfer M, et al. Tromethamine buffer modifies the depressant effect of permissive hypercapnia on myocardial contractility in patients with acute respiratory distress syndrome. Am J Respir Crit Care Med 2000;162:1361-5.
  6. Hotchkiss JR Jr, Blanch L, Murias G, Adams AB, Olson DA, Wangensteen OD, et al. Effects of decreased respiratory frequency on ventilator-induced lung injury. Am J Respir Crit Care Med 2000;161:463-8.
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