Indian Journal of Critical Care Medicine

Register      Login

SEARCH WITHIN CONTENT

FIND ARTICLE

Volume / Issue

Online First

Archive
Related articles

VOLUME 19 , ISSUE 7 ( 2015 ) > List of Articles

CASE REPORT

Epstein-Barr virus infection-Related hemophagocytic lymphohistiocytosis

Sumit Singh, Navin Kumar, Smita Sarma

Keywords : Epstein-Barr virus, hemophagocytic lymphohistiocytosis, relapsing-remitting multiple sclerosis

Citation Information : Singh S, Kumar N, Sarma S. Epstein-Barr virus infection-Related hemophagocytic lymphohistiocytosis. Indian J Crit Care Med 2015; 19 (7):416-418.

DOI: 10.4103/0972-5229.160290

License: CC BY-ND 3.0

Published Online: 01-06-2016

Copyright Statement:  Copyright © 2015; The Author(s).


Abstract

We report a case of 27-year-old female diagnosed with hemophagocytic lymphohistiocytosis (HLH) following a recent Epstein-Barr virus (EBV) infection. A known case of relapsing remitting multiple sclerosis on corticosteroids for last 6 months presented to the critical care unit with fever, maculopapular rash and difficulty in breathing. A rapid and correct diagnosis with the precise treatment led to complete recovery of this patient. The HLH is a rare complication of primary EBV infection.


PDF Share
  1. Mischler M, Fleming GM, Shanley TP, Madden L, Levine J, Castle V, et al. Epstein-Barr virus-induced hemophagocytic lymphohistiocytosis and X-linked lymphoproliferative disease: A mimicker of sepsis in the pediatric intensive care unit. Pediatrics 2007;119:e1212-8.
  2. Henter JI, Horne A, Aricó M, Egeler RM, Filipovich AH, Imashuku S, et al. HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer 2007;48:124-31.
  3. Janka GE. Hemophagocytic syndromes. Blood Rev 2007;21:245-53.
  4. Fisman D. Haemophagocytic syndromes and Infection. Emerg Infect Dis 2000;6:600-8.
  5. Risma K, Jordan MB. Hemophagocytic lymphohistiocytosis: Updates and evolving concepts. Curr Opin Pediatr 2012;24:9-15.
  6. Olaya M, Alsina L, de Sevilla MF, Catalá A, López-Ramos MG, Martín Mateos MA, et al. Epstein-Barr virus infection triggering a haemophagocytic syndrome. Allergol Immunopathol (Madr) 2014;42:627-9.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.