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VOLUME 20 , ISSUE 2 ( 2016 ) > List of Articles


Warfarin-induced raised international normalized ratio is further prolonged by pantoprazole

Nand Kishore Dubey

Citation Information : Dubey NK. Warfarin-induced raised international normalized ratio is further prolonged by pantoprazole. Indian J Crit Care Med 2016; 20 (2):127-128.

DOI: 10.4103/0972-5229.175934

License: CC BY-ND 3.0

Published Online: 01-08-2013

Copyright Statement:  Copyright © 2016; The Author(s).


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  2. Heimark LD, Wienkers L, Kunze K, Gibaldi M, Eddy AC, Trager WF, et al. The mechanism of the interaction between amiodarone and warfarin in humans. Clin Pharmacol Ther 1992;51:398-407.
  3. Li XQ, Andersson TB, Ahlström M, Weidolf L. Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities. Drug Metab Dispos 2004;32:821-7.
  4. Duursema L, Müller FO, Schall R, Middle MV, Hundt HK, Groenewoud G, et al. Lack of effect of pantoprazole on the pharmacodynamics and pharmacokinetics of warfarin. Br J Clin Pharmacol 1995;39:700-3.
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