Statin-induced rhabdomyolysis in patient with renal failure and underlying undiagnosed hypothyroidism

Sachinkumar N. Ambapkar; Naresh Shetty; Arpita Dwivedy; Harshad Onkarrao Malve

doi:10.4103/0972-5229.182210

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Statin-induced rhabdomyolysis in patient with renal failure and underlying undiagnosed hypothyroidism

Sachinkumar N. Ambapkar, Naresh Shetty, Arpita Dwivedy, Harshad Onkarrao Malve

Keywords : Atorvastatin, foot drop, myopathy, myositis

Citation Information : Ambapkar SN, Shetty N, Dwivedy A, Malve HO. Statin-induced rhabdomyolysis in patient with renal failure and underlying undiagnosed hypothyroidism. Indian J Crit Care Med 2016; 20 (5):305-307.

DOI: 10.4103/0972-5229.182210

License: CC BY-ND 3.0

Published Online: 01-05-2016

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Abstract

Rhabdomyolysis is a syndrome characterized by muscle necrosis which causes the release of myoglobin into the bloodstream. The manifestations of this syndrome range from asymptomatic elevation of serum muscle enzymes to life-threatening cases associated with extremely high enzyme levels, electrolyte imbalance, and acute renal failure. Symptoms of rhabdomyolysis include dark urine, muscle weakness, and fatigue. Statins are commonly used drugs for the prevention and management of dyslipidemia. We present an interesting and critical case on statin-induced rhabdomyolysis with renal failure and previously undiagnosed idiopathic hypothyroidism.

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