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VOLUME 20 , ISSUE 8 ( 2016 ) > List of Articles

BRIEF COMMUNICATION

Acute respiratory failure in scrub typhus patients

Jyoti Narayan Sahoo, Yogesh Harde

Keywords : Acute respiratory distress syndrome, respiratory failure, scrub typhus

Citation Information : Sahoo JN, Harde Y. Acute respiratory failure in scrub typhus patients. Indian J Crit Care Med 2016; 20 (8):480-484.

DOI: 10.4103/0972-5229.188206

License: CC BY-ND 3.0

Published Online: 01-08-2016

Copyright Statement:  Copyright © 2016; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Respiratory failure is a serious complication of scrub typhus. In this prospective study, all patients with a diagnosis of scrub typhus were included from a single center Intensive Care Unit (ICU). Demographic, clinical characteristics, laboratory, and imaging parameters of these patients at the time of ICU admission were compared. Of the 55 scrub typhus patients, 27 (49%) had an acute respiratory failure. Seventeen patients had acute respiratory distress syndrome, and ten had cardiogenic pulmonary edema. Respiratory supported patients were older had significant chronic lungs disease and high severity illness scores (Acute Physiology and Chronic Health Evaluation-II and Sequential Organ Failure Assessment score). At ICU admission, these patients presented with more deranged laboratory markers, including high bilirubin, high creatine kinase, high lactate, metabolic acidosis, low serum albumin, and presence of ascites. The average ICU and hospital stay were 4.27 ± 2.74 and 6.53 ± 3.52 days, respectively, in the respiratory supported group. Three patients died in respiratory failure group, while only one patient died in nonrespiratory failure group.


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