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VOLUME 17 , ISSUE 2 ( April, 2013 ) > List of Articles


Two cases of asystolic cardiac arrests managed with therapeutic hypothermia

Piyush Narayan Mallick, Surjya Prasad Upadhyay, Raj Kumar A Singh

Keywords : Asystole, prolonged cardiac arrest, return of spontaneous circulation, therapeutic hypothermia, and neurological outcome

Citation Information : Mallick PN, Upadhyay SP, Singh RK. Two cases of asystolic cardiac arrests managed with therapeutic hypothermia. Indian J Crit Care Med 2013; 17 (2):113-115.

DOI: 10.4103/0972-5229.114821

License: CC BY-ND 3.0

Published Online: 01-05-2014

Copyright Statement:  Copyright © 2013; The Author(s).


Poor neurological outcome is a common sequel of prolonged cardiac arrest. Although Therapeutic Hypothermia (TH) for neuroprotection has been a subject for research for over Half a century, its use has been limited because of many controversies and lack of clear guidelines. However for over two decades there has been a revival of interest in mild therapeutic hypothermia (32-34°C) for neuroprotection. However its use after primary asystolic cardiac arrest has been questioned. Herein presenting two cases of prolonged asystolic arrest (39 minutes and 25 minutes); where therapeutic hypothermia was successfully used in following prolonged cardio pulmonary resuscitation. On patients who were in deep coma after resuscitation, TH was applied for 24 hours as per institutional protocol with full neurological recovery in both the cases. Therapeutic hypothermia might have a potential role in even in non-shockable arrests and should be considered in every successful cardiopulmonary resuscitation with poor neurological status.

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