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VOLUME 17 , ISSUE 2 ( April, 2013 ) > List of Articles


Two unusual complications of neuroleptic malignant syndrome

A. Ahmad, C. A. Harrison, H. G. Davies

Keywords : Brachial plexus injury, compartment syndrome, neuroleptic malignant syndrome

Citation Information : Ahmad A, Harrison CA, Davies HG. Two unusual complications of neuroleptic malignant syndrome. Indian J Crit Care Med 2013; 17 (2):116-118.

DOI: 10.4103/0972-5229.114823

License: CC BY-ND 3.0

Published Online: 01-05-2014

Copyright Statement:  Copyright © 2013; The Author(s).


Neuroleptic malignant syndrome (NMS) is a rare but well described complication of the administration of antipsychotic agents. Compartment syndrome, with increased pressures within the confined space of fascial sheaths leading to compression damage of the contained tissue, similarly is well described. Brachial plexus injuries caused by patient malposition are also very rare but a few cases have been reported. We report a case where these three complications occurred together. This was attributable to the patient developing NMS whilst asleep in the prone position overnight.

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  1. Adnet P, Lestavel P, Krivosic-Horber R. Neuroleptic malignant syndrome. Br J Anaesth 2000;85:129-35.
  2. Stotz M, Thümmler D, Schürch M, Renggli JC, Urwyler A, Pargger H. Fulminant neuroleptic malignant syndrome after perioperative withdrawal of anti Parkinsonian medication. Br J Anaesth 2004;93:868-71.
  3. Shalev A, Hermesh H, Munitz H. Mortality from neuroleptic malignant syndrome. J Clin Psychiatry 1989;50:18-25.
  4. Hassan S, Buckley P. Novel antipsychotics and the neuroleptic malignant syndrome: A review and critique. Am J Psych 1998;155:1113-6.
  5. Guerra R. Sympathoadrenal hyperactivity and the aetiology of neuroleptic malignant syndrome. Am J Psych 1999;156:169-80.
  6. O′Donnell CJ, Beck DH, Taylor BL, Smith GB. Upper limb compartment syndromes: A complication of malignant hyperthermia in a patient with ill-defined myopathy. Br J Anaesth 1995;74:343-4.
  7. Goettler CE, Pryor JP, Reilly PM. Brachial plexopathy after prone positioning. Crit Care 2002;6:540-42.
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