VOLUME 17 , ISSUE 5 ( October, 2013 ) > List of Articles
Avdhesh Bansal, Vikas Sikri
Keywords : Granulocyte macrophage colony stimulating factor, pulmonary alveolar proteinosis, Trans Bronchial Lung Biopsy, whole-lung lavage
Citation Information : Bansal A, Sikri V. A case of pulmonary alveolar proteinosis treated with whole lung lavage. Indian J Crit Care Med 2013; 17 (5):314-317.
DOI: 10.4103/0972-5229.120327
License: CC BY-ND 3.0
Published Online: 01-10-2013
Copyright Statement: Copyright © 2013; The Author(s).
Pulmonary alveolar proteinosis represents a rare syndrome characterized by the accumulation of proteinaceous phospholipid-laden material in the alveoli. This leads to impaired gas exchange and arterial hypoxemia of varying degrees. The diagnosis is confirmed by lung biopsy. Sequential whole-lung lavage (WLL) first described in 1963 is the standard of care. We report a case of a male diagnosed of having pulmonary alveolar proteinosis (PAP) on transbroncial lung biopsy (TBLB). He was treated with sequential WLL (Left followed by right, Left being more involved on chest X-ray) followed by recombinant GM-CSF, with good result.
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