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VOLUME 18 , ISSUE 3 ( March, 2014 ) > List of Articles


Lemierre′s syndrome: An often missed life-threatening infection

Narat Srivali, Patompong Ungprasert, Wonngarm Kittanamongkolchai, Nischala Ammannagari

Keywords : Anaerobic infection, fusobacterium, Lemierre′s syndrome, postanginal sepsis

Citation Information : Srivali N, Ungprasert P, Kittanamongkolchai W, Ammannagari N. Lemierre′s syndrome: An often missed life-threatening infection. Indian J Crit Care Med 2014; 18 (3):170-172.

DOI: 10.4103/0972-5229.128708

License: CC BY-ND 3.0

Published Online: 01-12-2014

Copyright Statement:  Copyright © 2014; The Author(s).


Lemierre′s syndrome is an uncommon, but fatal infection of the internal jugular vein (IJV) that is usually caused by Fusobacteirum necrophorum although a wide range of bacteria has been reported as causative agents. Typical symptoms include fever, sore throat, neck swelling, pulmonary symptoms and arthralgia; however, the diagnosis of this infection is frequently overlooked as initial manifestation might be subtle and non-specific. Definite diagnosis requires positive blood culture and radiological evidence of thrombus in the IJV. We describe a case of a patient with Lemierre′s syndrome who was initially misdiagnosed with viral upper respiratory tract infection. High index of suspicion is pivotal to the diagnosis of this infection and Lemierre′s syndrome should always be considered as a potential cause of sepsis in an otherwise healthy patient.

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  1. Kuppalli K, Livorsi D, Talati NJ, Osborn M. Lemierre′s syndrome due to Fusobacterium necrophorum. Lancet Infect Dis 2012;12:808-15.
  2. Lustig LR, Cusick BC, Cheung SW, Lee KC. Lemierre′s syndrome: Two cases of postanginal sepsis. Otolaryngol Head Neck Surg 1995;112:767-72.
  3. Dorfman A, Shokoohi H, Taheri MR. Lemierre′s syndrome and rapidly deteriorating respiratory failure in the emergency department. Am J Emerg Med 2012;30:1658.e5-7.
  4. Golpe R, Marín B, Alonso M. Lemierre′s syndrome (necrobacillosis). Postgrad Med J 1999;75:141-4.
  5. Forrester LJ, Campbell BJ, Berg JN, Barrett JT. Aggregation of platelets by Fusobacterium necrophorum. J Clin Microbiol 1985;22:245-9.
  6. Chirinos JA, Lichtstein DM, Garcia J, Tamariz LJ. The evolution of Lemierre syndrome: Report of 2 cases and review of the literature. Medicine (Baltimore) 2002;81:458-65.
  7. Hagelskjaer LH, Prag J, Malczynski J, Kristensen JH. Incidence and clinical epidemiology of necrobacillosis, including Lemierre′s syndrome, in Denmark 1990-1995. Eur J Clin Microbiol Infect Dis 1998;17:561-5.
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