Indian Journal of Critical Care Medicine

Register      Login

SEARCH WITHIN CONTENT

FIND ARTICLE

Volume / Issue

Online First

Archive
Related articles

VOLUME 18 , ISSUE 4 ( April, 2014 ) > List of Articles

CASE REPORT

Guillain-Barre syndrome complicated by acute fatal rhabdomyolysis

Nitin Verma, Amrish Saxena, Vineeta Singh

Keywords : Acute kidney injury, creatine kinase, Guillain-Barre syndrome, hyperkalemia, rhabdomyolysis

Citation Information : Verma N, Saxena A, Singh V. Guillain-Barre syndrome complicated by acute fatal rhabdomyolysis. Indian J Crit Care Med 2014; 18 (4):241-243.

DOI: 10.4103/0972-5229.130577

License: CC BY-ND 3.0

Published Online: 01-04-2014

Copyright Statement:  Copyright © 2014; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Guillain-Barre syndrome (GBS) is a heterogenous group of peripheral-nerve disorders with similar clinical presentation characterized by acute, self-limited, progressive, bilateral and relatively symmetric ascending flaccid paralysis, which peaks in 2-4 weeks and then subsides. The usual complications, which occur in a patient of GBS are pneumonia, sepsis, pulmonary embolism, respiratory insufficiency and cardiac arrest. The clinical course of GBS complicated by acute rhabdomyolysis is extremely rare. We present the case of GBS with marked elevation in serum creatine kinase, serum myoglobin levels and persistent hyperkalemia as a result of associated acute rhabdomyolysis.


PDF Share
  1. Yuki N, Hartung HP. Guillain-Barré syndrome. N Engl J Med 2012;366:2294-304.
  2. Asbury AK. Diagnostic considerations in Guillain-Barré syndrome. Ann Neurol 1981;9 Suppl: 1-5.
  3. Ropper AH, Shahani BT. Pain in Guillain-Barré syndrome. Arch Neurol 1984;41:511-4.
  4. Vanholder R, Sever MS, Erek E, Lameire N. Rhabdomyolysis. J Am Soc Nephrol 2000;11:1553-61.
  5. Bosch X, Poch E, Grau JM. Rhabdomyolysis and acute kidney injury. N Engl J Med 2009;361:62-72.
  6. Chen SC, Liu KS, Chang HR, Lee YT, Chen CC, Lee MC. Rhabdomyolysis following pandemic influenza A (H1N1) infection. Neth J Med 2010;68:317-9.
  7. Lim M, Goh HK. Rhabdomyolysis following dengue virus infection. Singapore Med J 2005;46:645-6.
  8. Fodili F, van Bommel EF. Severe rhabdomyolysis and acute renal failure following recent Coxsackie B virus infection. Neth J Med 2003;61:177-9.
  9. Satoh J, Okada K, Kishi T, Nagayama S, Kuroda Y. Cramping pain and prolonged elevation of serum creatine kinase levels in a patient with Guillain-Barré syndrome following campylobacter jejuni enteritis. Eur J Neurol 2000;7:107-9.
  10. Scott AJ, Duncan R, Henderson L, Jamal GA, Kennedy PG. Acute rhabdomyolysis associated with atypical Guillain-Barré syndrome. Postgrad Med J 1991;67:73-4.
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.