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VOLUME 10 , ISSUE 2 ( April, 2006 ) > List of Articles


Goodpasture′s disease: A case report from South India

Nitin Kumar Dumeer, Aruna Kumari Pragaya, T. Manmadha Rao, C. Sundaram

Keywords : Goodpasture′s disease, pulmonary renal syndrome

Citation Information : Dumeer NK, Pragaya AK, Manmadha Rao T, Sundaram C. Goodpasture′s disease: A case report from South India. Indian J Crit Care Med 2006; 10 (2):115-116.

DOI: 10.4103/0972-5229.25925

License: CC BY-ND 3.0

Published Online: 01-07-2010

Copyright Statement:  Copyright © 2006; The Author(s).


A 28-year-old male died following massive hemoptysis at Nizam′s Institute of Medical Sciences, Hyderabad. He presented with recurrent hemoptysis and hematuria. The lungs showed alveolar hemorrhages with hemosiderin laden macrophages. Kidneys showed focal proliferative glomerulonephritis with crescents. Direct immunoflouresence of the kidney showed linear deposition of IgG and granular deposits of C3.

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  1. Bolton KW. Goodpasture′s syndrome. Kidney Int 1996:50;1753-66.
  2. Turner AN, Rees AJ. Antiglomerular basement membrane disease. In Oxford textbook of clinical nephrology. editor, Davison AM et al. Oxford University Press: New York; 2005. p. 579-600.
  3. Vasudev AS, Kabra SK, Bagga A, Moudgil A, Vijayaraghavan M, Srivastava R et al. Goodpasture′s syndrome. Indian Pediatr 1990;27:984-7.
  4. Mukherjee S, Chugh KS, Bhagwat AG. Goodpasture′s syndrome. J Indian Med Assoc 1978;16:100-1.
  5. Kalluri R. Goodpasture′s syndrome. Kidney Int 1999;55:1120-2.
  6. Macdonald BA, Sund M, Grant MA, Pfaff KL, Holthaus K, Zon LI, et al. Zebra fish to humans: Evolution of the {alpha} 3- chain and emergence of the autoimmune epitopes of type IV collagen associated with Goodpasture′s syndrome. Blood 2005.
  7. Gallagher H, Kwan JT, Jayne DR. pulmonary renal syndrome: A 4-year, single- center experience. Am J Kidney Dis 2002;39:42-7.
  8. Herody M, Bobrie G, Gouarin C, Grunfeld JP, Noel LH. Anti - GBM disease: predictive value of clinical, histologic and serologic data. Clin Nephrol 1993;40:249-55.
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