Indian Journal of Critical Care Medicine

Register      Login

SEARCH WITHIN CONTENT

FIND ARTICLE

Volume / Issue

Online First

Archive
Related articles

VOLUME 11 , ISSUE 2 ( April, 2007 ) > List of Articles

ORIGINAL ARTICLE

Study of antibiotic sensitivity pattern of methicillin-resistant Staphylococcus aureus

Manish Patel, Summaiya Mulla, Latika Shah, Geeta Vaghela

Keywords : Antibiotics, coagulase positive staphylococci, methicillin resistant Staphylococcus aureus

Citation Information : Patel M, Mulla S, Shah L, Vaghela G. Study of antibiotic sensitivity pattern of methicillin-resistant Staphylococcus aureus. Indian J Crit Care Med 2007; 11 (2):99-101.

DOI: 10.4103/0972-5229.33394

License: CC BY-ND 3.0

Published Online: 01-04-2007

Copyright Statement:  Copyright © 2007; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

There is a growing concern about the rapid rise in resistance of Staphylococcus aureus to antimicrobial agents. Our objective was to determine the prevalence and pattern of antibiotic sensitivity among Methicillin-resistant and Methicillin-sensitive Staphylococcus aureus in Surat, South Gujarat, India. Covering the period of three months from August-2004 to October 2004, we processed the samples of Pus, Urine, Blood, high vaginal swabs, Sputum, throat swabs, drains and ear swabs received from New Civil Hospital, Surat. Total 135 Staphylococci were isolated, out of which, 48 (35.55%) were coagulase positive. These coagulase positive Staphylococci isolates were screened for Methicillin-resistance by a slide latex agglutination kit for the rapid detection of PBP2′ (Penicillin binding protein 2a). Sensitivity to amikacin, erythromycin, clindamycin and tetracycline were also carried out following Kirbey Bauer disc diffusion method. Methicillin resistance among the Staphylococcus aureus isolates was 39.5%. Resistance to all antibiotics tested among the Methicillin-resistance and Methicillin-sensitive, staphylococci was found to be 26.3% and 6.8% respectively, which is statistically significant. Methicillin-resistance is a useful marker in selecting appropriate antimicrobial agents for treatment of infections caused by S. aureus changing pattern of resistance of S. aureus makes its periodic surveillance mandatory.


PDF Share
  1. Antibacterial resistance pattern and frequency of Methicillin resistant Staphylococcus aureus. Irn J Med Sci 1997;22:93.
  2. Antimicrobial susceptibility pattern among Methicillin reistant Staphylococus isolates in Assam. Indian J Med Microbiol 2001;19:138-40.
  3. Prevalence of Methicillin resistant Staphylococcus aureus in a tertiary referral hospital in Eastern Utter Pradesh. Indian J Med Microbiol 2003;21:49-51.
  4. Prevalence and pattern of antibiotic sensitivity of Methicillin sensitive and resistant Staphylococcus aureus in Shiraz-Iran. Irn J Med Sci 2000;25:1-8.
  5. Antibiogram sensitivity pattern of Methicillin resistant Staphylococcus aureus isolates from pus sample. Pak J Biol Sci 2002;5:491-3.
  6. Study of Methicillin resistant S. aureus (MRSA) ilolates from high risk patients. Indian J Med Microbiol 2001;19:13-6.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.