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VOLUME 13 , ISSUE 1 ( March, 2009 ) > List of Articles


Aluminum phosphide poisoning: Effect of correction of severe metabolic acidosis on patient outcome

S. Jaiswal, R. K. Verma, N. Tewari

Keywords : Aluminum phosphide, arterial blood gases, poisoning, sodium bicarbonate

Citation Information : Jaiswal S, Verma RK, Tewari N. Aluminum phosphide poisoning: Effect of correction of severe metabolic acidosis on patient outcome. Indian J Crit Care Med 2009; 13 (1):21-24.

DOI: 10.4103/0972-5229.53111

License: CC BY-ND 3.0

Published Online: 01-04-2012

Copyright Statement:  Copyright © 2009; The Author(s).


Forty patients of aluminum phosphide poisoning who were admitted to the ICU of Sir Sunder Lal Hospital, Banaras Hindu University, were studied. Restlessness, excessive thirst, shock, arrhythmias, tachypnoea, and severe metabolic acidosis were the common clinical findings. Only repeated and full correction with intravenous sodium bicarbonate was able to cope up with the severity and rapidity of acidosis. There was no significant change in blood pressure, pulse rate, and respiratory rate after full correction but gradually pulse and systolic blood pressure settled after ionotropic support in the survivors. There was significant improvement from 30.36% in the case when only half correction was done, as has been the common practice, to 57.5%, when full correction of metabolic acidosis was done.

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  1. Pesticide poisoning. Natl Med J India 2007;20:182-91
  2. K. Cardiovascular manifestations in aluminium phosphide poisoning with special reference to echocardiographic changes. J Assoc Physicians India 1995;43:773-4,779-80.
  3. Acute phosphine poisoning following injestion of aluminium phosphide. Hum Toxicol 1988;7:343-5.
  4. Spot diagnosis of aluminium phosphide ingestion: An application of a simple test. J Assoc Physicians India 1989;37:219-20.
  5. Cardiovascular manifestations of aluminium phosphide intoxication. J Assoc Physicians India 1989;37:590-2.
  6. ECG changes in aluminium phosphide and organo phosphorus poisoning. Indian Practitioner 1999;52:249-52.
  7. Aluminium phosphide poisoning in a young adult: A suicidal cardiotoxin simulating myocardial ischaemia. J Indian Acad Clin Med 2004;5:369.
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