Cerebritis: An unusual complication of Klebsiella pneumoniae
Mainak Majumdar, David C. Simes, Ramesh D. Prabha
Keywords :
Alcohol, cerebritis, Klebsiella
Citation Information :
Majumdar M, Simes DC, Prabha RD. Cerebritis: An unusual complication of Klebsiella pneumoniae. Indian J Crit Care Med 2009; 13 (1):37-40.
Cerebritis is part of a continuum of brain infection and is difficult to diagnose. Cerebritis caused by Klebsiella in immunocompetent adults without predisposing factors such as neurosurgery or penetrating brain injury has not been reported before. We report a case of Klebsiella cerebritis in an adult patient with a proven extracranial focus of infection. We suggest considering cerebritis as a differential diagnosis for altered level of consciousness in patients of severe sepsis, even if an extracranial source of infection is proven.
Brain abscess: A study of 45 consecutive cases. Medicine (Baltimore) 1986;65:415-31.
Meningitis caused by gram-negative bacilli. Ann Intern Med 1980;93:253-60.
Rapid glia expression and release of proinflammatory cytokines in experimental Klebsiella pneumoniae meningoencephalitis. Exp Neurol 2007;205:270-8.
Community-acquired spontaneous bacterial meningitis in patients with alcoholic liver disease. J Formos Med Assoc 2003;102:653-5.
Effects of ethanol on cytokine production after surgery in a murine model of gram-negative pneumonia. Alcohol Clin Exp Res 2008;32:331-8.
Effect of alcohol consumption on host release of interleukin-17 during pulmonary infection with Klebsiella pneumoniae. Alcohol Clin Exp Res 2001;25:872-81.
Acute alcohol intoxication suppresses the interleukin 23 response to Klebsiella pneumoniae infection. Alcohol Clin Exp Res 2006;30:1200-7.
Acute alcohol intoxication suppresses the pulmonary negative CXC chemokine response to lipopolysaccharides. Alcohol 2007;41:325-33.
The prognostic factors of adult gram-negative bacillary meningitis. J Hosp Infect 1998;40:27-34.
Clinical stages of human brain abscesses on serial CT scans after contrast infusion: Computerized tomographic, neuropathological and clinical correlations. J Neurosurg 1983;59:972-89.
