Indian Journal of Critical Care Medicine

Register      Login



Volume / Issue

Online First

Related articles

VOLUME 13 , ISSUE 3 ( September, 2009 ) > List of Articles


Critical care issues in adult liver transplantation

Dharmesh Kapoor, Ravichandra Raya, M. Subrahmanyam, B. Sukanya

Keywords : Adult liver transplantation, critical care, orthotopic liver transplantation

Citation Information : Kapoor D, Raya R, Subrahmanyam M, Sukanya B. Critical care issues in adult liver transplantation. Indian J Crit Care Med 2009; 13 (3):113-119.

DOI: 10.4103/0972-5229.58535

License: CC BY-ND 3.0

Published Online: 01-07-2012

Copyright Statement:  Copyright © 2009; The Author(s).


Over the last decade, liver transplantation has become an operational reality in our part of the world. As a result, clinicians working in an intensive care unit are more likely to be exposed to these patients in the immediate postoperative period, and thus, it is important that they have a working knowledge of the common complications, when they are likely to occur, and how to deal with them. The main focus of this review is to address the variety of critical care issues in liver transplant recipients and to impress upon the need to provide favorable circumstances for the new liver to start functioning and maintain the function of other organs to aid in this process.

PDF Share
  1. Predictive factors for early mortality following liver transplantation. Clin Transplant 2003;17:401-11.
  2. Adult living donor versus deceased donor liver transplantation: A 6-year single center experience. Am J Transplant 2005;5:149.
  3. Basiliximab in a triple-drug regimen with tacrolimus and steroids in liver transplantation. Transplant Proc 2005;37:2611.
  4. Banff schema for grading liver allograft rejection: An international consensus document. Hepatology 1997;25:658-63.
  5. Hepatology 2000;31:792-9.
  6. Successful use of an enhanced immunosuppressive protocol with plasmapheresis for ABO-incompatible mismatched grafts. Transplantation 1995;59:986-90.
  7. Hepatic artery thrombosis after orthotopic liver transplantation: A review of nonsurgical causes. Liver Transpl 2001;7:75-81.
  8. Vascular complications after orthotopic liver transplantation. Am J Surg 1991;161:76-83.
  9. Anatomical variations and surgical strategies in right lobe living donor liver transplantation: Lessons from 120 cases. Transplantation 2002;73:1896-903.
  10. Living-donor liver transplantation in adults: Tokyo Univerity experience. J Hepatobiliary Pancreat Surg 2003;10:1-4.
  11. An endoscopic approach to biliary complications following orthotopic liver transplantation. Liver Int 2003;23:156-62.
  12. Post-liver transplantation myocardial dysfunction. Liver Transplant Surg 1998;4:399-403.
  13. Two-dimensional and dobutamine stress echocardiography in the preoperative assessment of patients with end-stage liver disease prior to orthotopic liver transplantation. Transplantation 1996;61:1180-8.
  14. Morbidity and mortality in patients with coronary artery disease undergoing orthotopic liver transplantation. Liver Transpl Surg 1996;2:426-30.
  15. Pulmonary hemodynamics in liver cirrhosis. Semin Respir Med 1985;7:164-71.
  16. Prevalence and reversibility of the hepatopulmonary syndrome after liver transplantation. The Cleveland Clinic experience. West J Med 1995;163:133-8.
  17. Etiology of acute pulmonary edema during liver transplantation: A series of cases with analysis of the edema fluid. Chest 2001;119:219-23.
  18. Effects of renal impairment on liver transplantation. Gastroenterology 1987;93:148-56.
  19. Renal dysfunction following orthotopic liver transplantation. Clin Transplant 1989;3:94-100.
  20. The kidney in liver transplantation. J Am Soc Nephrol 1993;4:129-36.
  21. Veno-venous bybass versus no bypass in orthotopic liver transplantation: Hemodynamic, metabolic and renal data. Transplant proc 1998;30:1871-73.
  22. Acute renal failure requiring renal replacement therapy after orthotopic liver transplantation. Transplantation Proceedings 2006;38:1141-2.
  23. An epidemiologic study of early renal replacement therapy after orthotopic liver transplantation. J Am Soc Nephrol 2002;13:228-33.
  24. The first 100 liver transplantations at the Mayo Clinic, Mayo Clin Proc 1989;64:84-94.
  25. Neurologic complications of liver transplantation in adults. Neurology 2003;61:1174-8.
  26. Perioperative neurological complications after liver transplantation are best predicted by pre-transplant hepatic encephalopathy. Neurocrit Care 2008; 8: 253-258.
  27. Intensive insulin therapy in the critically ill patients. N Engl J Med 2001;345:1359-67.
  28. Neurologic sequelae after treatment of severe hyponatremia: A multicenter perspective. J Am Soc Nephrol 1994;4:1522-30.
  29. Thrombelastography. Present and future perspectives in clinical practice. Minerva Anestesiol 2003;69:501- 9,509 -15.
  30. Thromboelastography-guided transfusion algorithm reduces transfusions in complex cardiac surgery. Anesth Analg 1999;88:312-9.
  31. Intraoperative changes in blood coagulation and thrombelastographic monitoring in liver transplantation. Anesth Analg 1985;64:888-96.
  32. Thromboelastogram monitoring in the perioperative period of hepatectomy for adult living liver donation. Liver Transpl 2004;10:289-94.
  33. Thromboelastography for monitoring prolonged hypercoagulability after major abdominal surgery. Anesth Analg 2001;92:572-7.
  34. Patterns of coagulopathy during liver transplantation: Experience with the first 75 cases using thrombelastography. Anaesth Intensive Care 1994;22:659-65.
  35. Outcomes of 385 adult-to-adult living donor liver transplant recipients. Ann Surg 2005;242:314-25.
  36. Infection in organ-transplant recipients. N Engl J Med 2005;338:24.
  37. Am J Transplant 2004;4:110.
  38. Infections in solid organ transplant Recipients. In: Mandell GL, Bennett JE, Dolin R, editors. Principles and Practice of Infectious Diseases. Philadelphia; Churchill Livingstone; 2000: P. 3148-58.
  39. The association between hepatitis C infection and survival after orthotopic liver transplantation. Gastroenterology 2002;122:889-96.
  40. Hepatitis B virus reinfection after orthotopic liver transplantation. Serological and clinical implications. J Hepatol 1992;14:104-11.
  41. Immunosuppression: Towards a logical approach in liver transplantation. Clin Exp Immunol 2005;139:2-10.
  42. Tacrolimus is effective in both dual and triple regimens after liver transplantation. Transplant Proc 2002;34:1529-30.
  43. Results of lis2t, a multicenter, randomized study comparing cyclosporine microemulsion with C2 monitoring and tacrolimus with C0 monitoring in de novo liver transplantation. Transplantation 2004;77:1632-8.
  44. The U.S. Multicenter FK506 Liver Study Group. N Engl J Med 1994;331:1110-5.
  45. Tacrolimus versus microemulsified ciclosporin in liver transplantation: The TMC randomised controlled trial. Lancet 2002;360:1119-25.
  46. Increased protein catabolism without hypermetabolism after human orthotopic liver transplantation. Surgery 1987;101:146-9.
  47. Liver transplantation: The benefits of nutrition therapy in the liver transplant patient. In: Klintmalm G, editor. Recent Developments in Transplantation Medicine: Vol. 3. Liver Transplantation. Glenview, IL: Physicians and Scientists Publishing Co; 1996: P. 81-100.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.