Indian Journal of Critical Care Medicine

Register      Login

SEARCH WITHIN CONTENT

FIND ARTICLE

Volume / Issue

Online First

Archive
Related articles

VOLUME 14 , ISSUE 2 ( April, 2010 ) > List of Articles

CASE REPORT

Successful renal transplantation after recovery from acute disseminated encephalomyelitis in a child with end-stage renal disease

Guruprasad Bhosale, Veena Shah, Hargovind Trivedi

Keywords : Acute disseminated encephalomyelitis, end-stage renal disease

Citation Information : Bhosale G, Shah V, Trivedi H. Successful renal transplantation after recovery from acute disseminated encephalomyelitis in a child with end-stage renal disease. Indian J Crit Care Med 2010; 14 (2):101-103.

DOI: 10.4103/0972-5229.68228

License: CC BY-ND 3.0

Published Online: 00-04-2010

Copyright Statement:  Copyright © 2010; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Acute disseminated encephalomyelitis (ADEM), seen mostly in children, is an acute demyelinating disease, affecting mainly the white matter of brain and spinal cord. We report an unusual case of ADEM in an 11-year old boy with end-stage renal disease, who underwent hemopoietic stem cell transplantation prior to renal transplantation. He needed admission to the intensive care unit and required mechanical ventilation. He responded to intravenous injection of steroids and upon recovery, underwent renal transplantation successfully.


PDF Share
  1. Tenembaum S, Chitnis T, Ness J, Hahn JS. Acute disseminated encephalomyelitis. Neurology 2007;68:S23-36.
  2. Kim SC, Jang HJ, Han DJ. Acute disseminated encephalomyelitis after renal transplantation in patients with positive Epstein-Barr virus antibody. Transplant Proc 1998;30:3139.
  3. Aboagye-Kumi M, Yango A, Fischer S, Donahue J, Morrissey P, Taylor N, et al. Acute disseminated encephalomyelitis in a renal transplant recipient: A case report. Transplant Proc 2008;40:1751-3.
  4. Bennetto L, Scolding N. Inflammatory/post-infectious encephalomyelitis. J Neurol Neurosurg Psychiatry 2004;75:22-8.
  5. Garg RK. Acute disseminated encephalomyelitis. Postgrad Med J 2003;79:11-7.
  6. Schwarz S, Mohr A, Knauth M, Wildemann B, Storch-Hagenlocher B. Acute disseminated encephalomyelitis: A follow-up study of 40 patients. Neurology 2001;56:1313-8.
  7. Woodard P, Helton K, McDaniel H, Khan RB, Thompson S, Hale G, et al. Encephalopathy in pediatric patients after allogeneic hematopoietic stem cell transplantation is associated with a poor prognosis. Bone Marrow Transplant 2004;33:1151-7.
  8. Faraci M, Lanino E, Dini G, Fondelli MP, Morreale G, Dallorso S, et al. Severe neurologic complications after hematopoietic stem cell transplantation in children. Neurology 2002;59:1895-904.
  9. Scheinberg P, Fischer SH, Li L, Nunez O, Wu CO, Sloand EM, et al. Distinct EBV and CMV reactivation patterns following antibody-based immunosuppression regimens in patients with severe aplastic anemia. Blood 2007;109:3219-24.
  10. Calistri E, Tiribelli M, Battista M, Michelutti A, Corbellino M, Viale P, et al. Epstein-Barr virus reactivation in a patient treated with anti-thymocyte globulin for severe aplastic anemia. Am J Hematol 2006;81:355-7.
  11. Dai MS, Kao WY, Shyu RY, Chao TY. Restoration of immunity and reactivation of hepatitis B virus after immunosuppressive therapy in a patient with severe aplastic anemia. J Viral Hepat 2004;11:283-5.
  12. Murthy SN, Faden HS, Cohen ME, Bakshi R. Acute disseminated encephalomyelitis in children. Pediatrics 2002;110:e21.
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.