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VOLUME 14 , ISSUE 2 ( April, 2010 ) > List of Articles


Interpretation of arterial blood gas

Pramod Sood, Sandeep Puri

Keywords : Arterial blood gas interpretation, ABG analysis, rules for rapid ABG analysis, Anion gap, Approach to mixed disorders

Citation Information : Sood P, Puri S. Interpretation of arterial blood gas. Indian J Crit Care Med 2010; 14 (2):57-64.

DOI: 10.4103/0972-5229.68215

License: CC BY-ND 3.0

Published Online: 01-12-2018

Copyright Statement:  Copyright © 2010; The Author(s).


Disorders of acid-base balance can lead to severe complications in many disease states, and occasionally the abnormality may be so severe as to become a life-threatening risk factor. The process of analysis and monitoring of arterial blood gas (ABG) is an essential part of diagnosing and managing the oxygenation status and acid-base balance of the high-risk patients, as well as in the care of critically ill patients in the Intensive Care Unit. Since both areas manifest sudden and life-threatening changes in all the systems concerned, a thorough understanding of acid-base balance is mandatory for any physician, and the anesthesiologist is no exception. However, the understanding of ABGs and their interpretation can sometimes be very confusing and also an arduous task. Many methods do exist in literature to guide the interpretation of the ABGs. The discussion in this article does not include all those methods, such as analysis of base excess or Stewart′s strong ion difference, but a logical and systematic approach is presented to enable us to make a much easier interpretation through them. The proper application of the concepts of acid-base balance will help the healthcare provider not only to follow the progress of a patient, but also to evaluate the effectiveness of care being provided.

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  1. Kellum JA. Making Strong Ion Difference the “Euro” for Bedside Acid-Base Analysis. Yearbook of Intensive Care and Emergency Medicine. Spr Ber Heid Publ 2005;5:675.
  2. Phillips B, Peretz DI. Blood Gas Pre-analytical considerations. Specimen collection, Calibration, and Controls (proposed guidelines). In: National Committee for Clinical Laboratory Standards. NCCLS publication. villanova PA, NCCLS; 1985.
  3. Bφrner U, Mόller H, Hφge R, Hempelmann G. The influence of anticoagulation on acid-base status and blood-gas analysis. Acta Anaesthesiol Scand 1984;28:277-9.
  4. Hutchison AS, Ralston SH, Dryburgh FJ, Small M, Fogelman I. Too much heparin: possible source of error in blood gas analysis. Br Med J 1983;287:1131-2.
  5. Toffaletti J, Ernst P, Hunt P, Abrams B. Dry electrolyte-balanced heparinized syringes evaluated for determining ionized calcium and other electrolytes in whole blood. Clin Chem 1991;37:1730-3.
  6. Woolf CR. Letter: Arterial blood gas levels after oxygen therapy. Chest 1976;69:808-9.
  7. Narins RG, Emmett M. Simple and mixed acid-base disorders: a practical approach. Medicine 1980;59:161-87.
  8. Marino PL. Arterial Blood Gas Interpretation. In; The ICU book, 2 nd edi. Lippincott, Williams and Wilkins Publishers;1998. P. 582-605.
  9. Bartter TC, Abouzgheib WB, Pratter MR, Irwin RS. Respiratory Failure- Part 1. In: Irwin and Rippe′s Intensive Care Medicine, 6 th edi. Lippincott, Williams and Wilkins Publishers; 2008. P. 485-9.
  10. Rao SM, Nagendranath V. Arterial Blood Gas Monitoring: Indian J Anaesth 2002;46:289-97.
  11. Chawla LS, Shih S, Davison D, Junker C, Seneff MG. Anion gap, anion gap corrected for albumin, base deficit and unmeasured anions in critically ill patients: implications on the assessment of metabolic acidosis and the diagnosis of hyperlactatemia. BMC Emerg Med 2008;8: 18.
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