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VOLUME 15 , ISSUE 2 ( April, 2011 ) > List of Articles

REVIEW ARTICLE

Vasopressin: Its current role in anesthetic practice

Saikat Sengupta, Jayeeta Roy, Jayanta K. Mitra

Keywords : Cardiopulmonary resuscitation, hemorrhagic shock, operating room, septic shock, vasopressin

Citation Information : Sengupta S, Roy J, Mitra JK. Vasopressin: Its current role in anesthetic practice. Indian J Crit Care Med 2011; 15 (2):71-77.

DOI: 10.4103/0972-5229.83006

License: CC BY-ND 3.0

Published Online: 01-04-2011

Copyright Statement:  Copyright © 2011; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

Vasopressin or antidiuretic hormone is a potent endogenous hormone, which is responsible for regulating plasma osmolality and volume. In high concentrations, it also raises blood pressure by inducing moderate vasoconstriction. It acts as a neurotransmitter in the brain to control circadian rhythm, thermoregulation and adrenocorticotropic hormone release. The therapeutic use of vasopressin has become increasingly important in the critical care environment in the management of cranial diabetes insipidus, bleeding abnormalities, esophageal variceal hemorrhage, asystolic cardiac arrest and septic shock. After 10 years of ongoing research, vasopressin has grown to a potential component as a vasopressor agent of the anesthesiologist′s armamentarium in the treatment of cardiac arrest and severe shock states.


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