Indian Journal of Critical Care Medicine

Register      Login

SEARCH WITHIN CONTENT

FIND ARTICLE

Volume / Issue

Online First

Archive
Volume  28 (2024)
Volume  27 (2023)
Volume  26 (2022)
Volume  25 (2021)
Volume  24 (2020)
Volume  23 (2019)
Volume  22 (2018)
Volume  21 (2017)
Volume  20 (2016)
Volume  19 (2015)
Volume  18 (2014)
Volume  17 (2013)
Volume  16 (2012)
Volume  15 (2011)
Volume  14 (2010)
Volume  13 (2009)
Volume  12 (2008)
Volume  11 (2007)
Volume  10 (2006)
Volume  9 (2005)
Volume  8 (2004)
Related articles

VOLUME 16 , ISSUE 1 ( January, 2012 ) > List of Articles

CASE REPORT

Anaphylaxis to artesunate?

P. S. Panda, D. K. Singh, S. K. Dube, G. R. Agrawal

Keywords : Anaphylaxis, artesunate, intraoperative

Citation Information : Panda PS, Singh DK, Dube SK, Agrawal GR. Anaphylaxis to artesunate?. Indian J Crit Care Med 2012; 16 (1):55-57.

DOI: 10.4103/0972-5229.94440

License: CC BY-ND 3.0

Published Online: 01-03-2018

Copyright Statement:  Copyright © 2012; The Author(s).


Abstract

Artesunate, an artemissin derivative is a highly efficacious and relatively safe antimalarial agent. Common adverse reactions to artemissin derivatives are nausea, vomiting, anorexia and dizziness. More serious but less-frequent toxic effects of artesunate use are neutropenia, anemia, hemolysis, elevated liver enzymes and severe allergic reactions. However, anaphylactic reaction to artesunate is a rare entity. Here, we report a case of anaphylaxis to parenteral artesunate and its successful management in a female patient to whom intravenous artesunate was administered during surgery under general anesthesia.

PDF Share
  1. Artesunate for the treatment of severe falciparum malaria. N Engl J Med 2008;358:1829-36.
  2. Guidelines for the treatment of malaria. Geneva: WHO; 2006. p. 16-40.
  3. Artesunate versus quinine for treatment of severe falciparum malaria: A randomized trial. Lancet 2005;366:717-25.
  4. The management of severe falciparum malaria. Am J Respir Crit Care Med 2003;167:673-4.
  5. Anaphylaxis during the perioperative period. Anesth Analg 2003;97:1381-95.
  6. Bacitracine irrigation: A cause of anaphylaxis in the operating room. Anesth Analg 2000;91:1027- 8.
  7. Anaphylaxis during anaesthesia: Results of a two-year survey in France. Results of a two-year survey in France. Br J Anaesth 2001;87:549-58.
  8. Anaphylactic reaction to intravenous artesunate. J Assoc Physicians India 2009;57:183-4.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.