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VOLUME 23 , ISSUE 8 ( August, 2019 ) > List of Articles


Glutamine Supplementation: The Pendulum Keeps on Swinging

Citation Information : Glutamine Supplementation: The Pendulum Keeps on Swinging. Indian J Crit Care Med 2019; 23 (8):350-351.

DOI: 10.5005/jp-journals-10071-23216

License: CC BY-NC 4.0

Published Online: 01-04-2019

Copyright Statement:  Copyright © 2019; The Author(s).


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  1. Singer P, Blaser AR, Berger MM, Alhazzani W, Calder PC, Casaer MP et al: ESPEN guideline on clinical nutrition in the intensive care unit. Clin Nutr. 2019 Feb;38(1):48–79.
  2. McClave SA, Martindale RG, Vanek VW, McCarthy M, Roberts P, Taylor Bet al: Guidelines for the Provision and Assessment of Nutrition Support Therapy in the Adult Critically Ill Patient: Society of Critical Care Medicine (SCCM) and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.). JPEN J Parenter Enteral Nutr. 2009 May-Jun;33(3):277–316.
  3. Amrein K, Schnedl C, Holl A, Riedl R, Christopher KB, Pachler C. et al. Effect of high-dose vitamin D3 on hospital length of stay in critically ill patients with vitamin D deficiency: the VITdAL-ICU randomized clinical trial. JAMA. 2014 Oct 15;312(15):1520–1530.
  4. Van den Berghe G. Low glutamine levels during critical illness--adaptive or maladaptive? N Engl J Med. 2013 Apr 18;368(16):1549–1550.
  5. Heyland D, Muscedere J, Wischmeyer PE, Cook D, Jones G et al. A randomized trial of glutamine and antioxidants in critically ill patients. Canadian Critical Care Trials Group. N Engl J Med. 2013 Apr 18;368(16):1489–1497.
  6. Novak F, Heyland DK, Avenell A, Drover JW, Su X. Glutamine supplementation in serious illness: a systematic review of the evidence. Crit Care Med 2002;30:2022–2029.
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