Citation Information :
Mohammed S, Gupta SK. Pulmonary Hyperinfection with Strongyloides stercoralis in an Immunocompetent Patient. Indian J Crit Care Med 2019; 23 (10):481-483.
Strongyloids stercoralis is a unique parasite as it has the capability of completing its life cycle entirely within the human host. The immune system of the host plays an important role in keeping the infection under control but when there is a breach in this system the infection may flare up and leads to hyperinfection. In immunocompetent patients, gastrointestinal manipulation could be an inciting trigger leading to translocation of larva into the systemic circulation and development of hyperinfection syndrome. We report a case where infection with S. stercoralis lead to hyperinfection in patient with intact immune system following laparotomy.
Mokhlesi B, Shulzhenko O, Garimella PS, Kuma L, Monti C. Pulmonary Strongyloidiasis: The Varied Clinical Presentations. Clin Pulm Med. 2004;11(1):6.
Genta RM. Global prevalence of strongyloidiasis: critical review with epidemiologic insights into the prevention of disseminated disease. Rev Infect Dis 1989;11:755–767.
Segarra-Newnham M. Manifestations, diagnosis and treatment of Strongyloides stercoralis infection. Ann Pharmacother. 2007;41(12):1992–2001.
Liu LX, Weller PF. Strongyloidiasis and other intestinal nematode infections. Infect Dis Clin North Am 1993;7:655–682.
Grove DI. Human strongyloidiasis. Adv Parasitol 1996;38:251–309.
Igra-Siegman Y, Kapila R, Sen P, Kaminski ZC, Louria DB. Syndrome of hyperinfection with Strongyloides stercoralis. Oxford J Med Clin Infec Dis. 1981;3:397– 407.
Woodring JH, Halfhill H 2nd, Berger R, Reed JC, Moser N. Clinical and imaging features of pulmonary strongyloidiasis. South Med J 1996;89:10–19.
Woodring JH, Halfhill H, Reed JC. Pulmonary strongyloidiasis: clinical and imaging features. Am J Roentgenol 1994;162:537–542.
Chan FLY, Kennedy B, Nelson R. Fatal Strongyloides hyperinfection syndrome in an immunocompetent adult with review of the literature. Internal Medicine Journal 2018;48:872–875.
Myint A, Chapman C, Almira-Suarez I, Mehta N. Strongyloides hyperinfection syndrome in an immunocompetent host resulting in bandemia and death. BMJ Case Rep 2017.