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VOLUME 23 , ISSUE 10 ( October, 2019 ) > List of Articles

CASE REPORT

Intraventricular Bleed Secondary to Intraventricular Antibiotics: A Case Report

Nikhat Sultana, K Subba Reddy, Munshi I Alam

Keywords : CNS infection, Intraventricular antibiotics

Citation Information : Sultana N, Reddy KS, Alam MI. Intraventricular Bleed Secondary to Intraventricular Antibiotics: A Case Report. Indian J Crit Care Med 2019; 23 (10):484-485.

DOI: 10.5005/jp-journals-10071-23268

License: CC BY-NC 4.0

Published Online: 01-10-2019

Copyright Statement:  Copyright © 2019; Jaypee Brothers Medical Publishers (P) Ltd.


Abstract

In case of multidrug resistant CNS infection use of intraventricular antibiotics are considered which have their own undesirable effects.1 An adult male patient who presented with multidrug resistant infection secondary to procedures done to facilitate to drain cerebrospinal fluid. Secondary to intraventricular antibiotic administration patient developed an intraparenchymal bleed with intraventricular extension; as a result of the bleed there was persistently raised intracranial pressure (ICP). The harmful effects of intraventricular antibiotics have to always be considered before taking a decision to start it. Appropriate precaution and low threshold of suspicion is required to rule out complications.


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  1. Lee JK, Seok JY, Lee JH, Choi E, Phi JH, Kim S-K, et al. Incidence and risk factors of ventriculoperitoneal shunt infections in children: a study of 333 consecutive shunts in 6 years. J Korean Med Sci. 2012;27(12):1563–1568. doi:10.3346/jkms.2012.27.12.1563
  2. Tunkel AR, Hartman BJ, Kaplan SL, Kaufman BA, Roos KL, Scheld WM, et al. Practice guidelines for the management of bacterial meningitis. Clinical Infection Disease. 2004;39(9):1267–1284. http://dx.doi.org/10.1086/425368. Medline:15494903 Google Scholar
  3. Schina M, Spyridi E, Daoudakis M, Mertzanos E, Korfias S. Successful treatment of multidrug-resistant Pseudomonas aeruginosa meningitis with intravenous and intrathecal colistin. Int J Infect Dis. 2006;10(2):178–179. http://dx.doi.org/10.1016/j.ijid.2005.03.005. Medline:16263315 Google Scholar
  4. De Bonis P, Lofrese G, Scoppettuolo G, Spanu T, Cultrera R, Labonia M, et al. Intraventricular versus intravenous colistin for the treatment of extensively drug resistant Acinetobacter baumannii meningitis. European journal of neurology: the official journal of the European Federation of Neurological Societies. 2016;23(1):68–75. doi:10.1111/ene.12789.
  5. Klingemann HG, Egbring R, Kaffarnik H. [Effects of polymyxin B and E (colistin) on blood coagulation, thrombocyte function, and fibrin structure (author's transl)] Arzneimittelforschung. 1980;30(10);1719–1721. PMID: 6254544.
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