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VOLUME 23 , ISSUE 12 ( December, 2019 ) > List of Articles


A Diagnostic Conundrum of Distributive Shock: Autoimmune Polyglandular Syndrome Type II

Monisha P Kumar, Braghadheeswar Thyagarajan, Nairmeen Haller, Daniela Ciltea

Keywords : Adrenal, Autoimmune, Polyglandular syndrome, Shock

Citation Information : Kumar MP, Thyagarajan B, Haller N, Ciltea D. A Diagnostic Conundrum of Distributive Shock: Autoimmune Polyglandular Syndrome Type II. Indian J Crit Care Med 2019; 23 (12):582-583.

DOI: 10.5005/jp-journals-10071-23297

License: CC BY-NC 4.0

Published Online: 01-08-2014

Copyright Statement:  Copyright © 2019; The Author(s).


Autoimmune polyglandular syndrome (AIPS) is a heterogeneous condition characterized by the loss of immune tolerance and resultant dysfunction of multiple endocrine organs. Although this condition is insidious in nature, it frequently presents initially as adrenal insufficiency (AI). For patients in shock, physicians routinely assess for infections, volume depletion as well as cardiogenic and iatrogenic causes of shock. However, the case described in this report emphasizes the need for high suspicion of AI syndrome when the etiology of shock remains unclear after primary assessment. A subsequent evaluation for autoimmune etiology, especially in young adults in appropriate clinical setting, may also be warranted.

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