Indian Journal of Critical Care Medicine

Register      Login

SEARCH WITHIN CONTENT

FIND ARTICLE

Volume / Issue

Online First

Archive
Related articles

VOLUME 24 , ISSUE S3 ( April, 2020 ) > List of Articles

INVITED ARTICLE

Epidemiology and Pathogenesis of Acute Kidney Injury in the Critically Ill Patients

Shilpushp J Bhosale

Keywords : Acute kidney injury, Epidemiology, Incidence of acute kidney injury, Pathogenesis, Sepsis

Citation Information : Bhosale S J. Epidemiology and Pathogenesis of Acute Kidney Injury in the Critically Ill Patients. Indian J Crit Care Med 2020; 24 (S3):84-89.

DOI: 10.5005/jp-journals-10071-23394

License: CC BY-NC 4.0

Published Online: 25-02-2014

Copyright Statement:  Copyright © 2020; The Author(s).


Abstract

HTML PDF Share
  1. Richet G. Early history of uremia. Kidney Int 1988;33(5):1013–1015. DOI: 10.1038/ki.1988.102.
  2. Bellomo R, Ronco C, Kellum JA, Mehta RL, Palevsky P, Acute Dialysis Quality Initiative Workgroup. Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the second international consensus conference of the acute dialysis quality initiative (ADQI) group. Crit Care 2004;8(4):R204–R212. DOI: 10.1186/cc2872.
  3. Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, et al. Acute kidney injury network: report of an initiative to improve outcomes in acute kidney injury. Crit Care 2007;11(2):R31. DOI: 10.1186/cc5713.
  4. Acute Kidney Injury Work Group. Kidney disease: improving global outcomes (KDIGO) - clinical practice guideline for acute kidney injury. Kidney Inter 2012;2(1):1–138. DOI: 10.1038/kisup.2012.1.
  5. Waikar SS, Curhan GC, Wald R, McCarthy EP, Chertow GM. Declining mortality in patients with acute renal failure, 1988 to 2002. J Am Soc Nephrol 2006;17(4):1143–1150. DOI: 10.1681/ASN.2005091017.
  6. Xue JL, Daniels F, Star RA, Kimmel PL, Eggers PW, Molitoris BA, et al. Incidence and mortality of acute renal failure in medicare beneficiaries, 1992 to 2001. J Am Soc Nephrol 2006;17(4):1135–1142. DOI: 10.1681/ASN.2005060668.
  7. Susantitaphong P, Cruz DN, Cerda J, Abulfaraj M, Alqahtani F, Koulouridis I, et al. World incidence of AKI: a meta-analysis. Clin J Am Soc Nephrol 2013;8(9):1482–1493. DOI: 10.2215/CJN.00710113.
  8. Hoste EAJ, Bagshaw SM, Bellomo R, Cely CM, Colman R, Cruz DN, et al. Epidemiology of acute kidney injury in critically ill patients: the multinational AKI-EPI study. Intensive Care Med 2015;41(8):1411–1423. DOI: 10.1007/s00134-015-3934-7.
  9. Peters E, Antonelli M, Wittebole X, Nanchal R, François B, Sakr Y, et al. A worldwide multicentre evaluation of the influence of deterioration or improvement of acute kidney injury on clinical outcome in critically ill patients with and without sepsis at ICU admission: results from the intensive care over nations audit. Crit Care 2018;22(1):188. DOI: 10.1186/s13054-018-2112-z.
  10. Paudel MS, Wig N, Mahajan S, Pandey RM, Guleria R, Sharma SK. A study of incidence of AKI in critically ill patients. Ren Fail 2012;34(10):1217–1222. DOI: 10.3109/0886022X.2012.723515.
  11. Gurjar M, Baronia AK, Azim A, Azim A, Bhadauria D, Baronia AK, et al. Septic acute kidney injury in critically ill Indian patients. Indian J Crit Care Med 2013;17(1):49–52. DOI: 10.4103/0972-5229.112147.
  12. Eswarappa M, Gireesh M, Ravi V, Kumar D, Dev G. Spectrum of acute kidney injury in critically ill patients: a single center study from South India. Indian J Nephrol 2014;24(5):280–285. DOI: 10.4103/0971-4065.132991.
  13. Reddy NP, Ravi KP, Dhanalakshmi P, Annigeri R, Ramakrishnan N, Venkataraman R. Epidemiology, outcomes and validation of RIFLE and AKIN criteria in acute kidney injury (AKI) in critically ill patients: Indian perspective. Ren Fail 2014;36(6):831–837. DOI: 10.3109/0886022X.2014.899432.
  14. Bhadade R, De'souza R, Harde MJ, Mehta KS, Bhargava P. A prospective study of acute kidney injury according to KDIGO definition and its mortality predictors. J Assoc Physicians India 2016;64(12):22–28.
  15. Sundar S, Korula S, Balakrishnan S, Paul V, Balagopal A. Acute kidney injury-incidence, prognostic factors, and outcome of patients in an intensive care unit in a tertiary center: a prospective observational study. Indian J Crit Care Med 2016;20(6):332–336. DOI: 10.4103/0972-5229.183904.
  16. Mahajan S, Sethi P, Anghan H, Soneja M, Wig N. Clinical and laboratory features associated with acute kidney injury in severe malaria. Indian J Crit Care Med 2018;22(10):718–722. DOI: 10.4103/ijccm.IJCCM_468_17.
  17. Saxena A, Meshram SV. Predictors of mortality in acute kidney injury patients admitted to medicine intensive care unit in a rural tertiary care hospital. Indian J Crit Care Med 2018;22(4):231–237. DOI: 10.4103/ijccm.IJCCM_462_17.
  18. Priyamvada P, Jayasurya R, Shankar V, Parameswaran S. Epidemiology and outcomes of acute kidney injury in critically ill: experience from a tertiary care center. Indian J Nephrol 2018;28(6):413–420. DOI: 10.4103/ijn.IJN_191_17.
  19. Mathew DMK, Radha DTR. Etiological factors and clinical profile of acute kidney injury in medical intensive care unit. Journal of Current Medical Research and Opinion 2019;2(11):350–366. DOI: 10.15520/jcmro.v2i11.235.
  20. Thadhani R, Pascual M, Bonventre JV. Acute renal failure. N Engl J Med 1996;334(22):1448–1460. DOI: 10.1056/NEJM199605303342207.
  21. Carlstrom M, Wilcox CS, Arendshorst WJ. Renal autoregulation in health and disease. Physiol Rev 2015;95(2):405–511. DOI: 10.1152/physrev.00042.2012.
  22. Kleinstreuer N, David T, Plank MJ, Endre Z. Dynamic myogenic autoregulation in the rat kidney: a whole-organ model. Am J Physiol Renal Physiol 2008;294(6):F1453–F1464. DOI: 10.1152/ajprenal.00426.2007.
  23. Green T, Gonzalez AA, Mitchell KD, Navar LG. The complex interplay between cyclooxygenase-2 and angiotensin II in regulating kidney function. Curr Opin Nephrol Hypertens 2012;21(1):7–14. DOI: 10.1097/MNH.0b013e32834d9d75.
  24. Venkatachalam MA, Griffin KA, Lan R, Geng H, Saikumar P, Bidani AK. Acute kidney injury: a springboard for progression in chronic kidney disease. Am J Physiol Renal Physiol. 2010;298(5):F1078–F1094. DOI: 10.1152/ajprenal.00017.2010.
  25. Prowle JR, Ishikawa K, May CN, Bellomo R. Renal blood flow during acute renal failure in man. Blood Purif 2009;28(3):216–225. DOI: 10.1159/000230813.
  26. Ravikant T, Lucas CE. Renal blood flow distribution in septic hyperdynamic pigs. J Surg Res 1977;22(3):294–298. DOI: 10.1016/0022-4804(77)90146-9.
  27. Brenner M, Schaer GL, Mallory DL, Suffredini AF, Parrillo JE. Detection of renal blood flow abnormalities in septic and critically ill patients using a newly designed indwelling thermodilution renal vein catheter. Chest 1990;98(1):170–179. DOI: 10.1378/chest.98.1.170.
  28. Zarjou A, Agarwal A. Sepsis and acute kidney injury. J Am Soc Nephrol 2011;22(6):999–1006. DOI: 10.1681/ASN.2010050484.
  29. Uchino S, Kellum JA, Bellomo R, Doig GS, Morimatsu H, Morgera S, et al. Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA 2005;294(7):813–818. DOI: 10.1001/jama.294.7.813.
  30. Huen SC, Cantley LG. Macrophage-mediated injury and repair after ischemic kidney injury. Pediatr Nephrol 2015;30(2):199–209. DOI: 10.1007/s00467-013-2726-y.
  31. Wan L, Bagshaw SM, Langenberg C, Saotome T, May C, Bellomo R. Pathophysiology of septic acute kidney injury: what do we really know? Crit Care Med 2008;36(Suppl):S198–S203. DOI: 10.1097/CCM.0b013e318168ccd5.
  32. Hotchkiss RS, Karl IE. The pathophysiology and treatment of sepsis. N Engl J Med 2003;348(2):138–150. DOI: 10.1056/NEJMra021333.
  33. Chow JC, Young DW, Golenbock DT, Christ WJ, Gusovsky F. Toll-like receptor-4 mediates lipopolysaccharide-induced signal transduction. J Biol Chem 1999;274(16):10689–10692. DOI: 10.1074/jbc.274.16.10689.
  34. Jang HR, Rabb H. Immune cells in experimental acute kidney injury. Nat Rev Nephrol 2015;11(2):88–101. DOI: 10.1038/nrneph.2014.180.
  35. Zuk A, Gershenovich M, Ivanova Y, MacFarland RT, Fricker SP, Ledbetter S. CXCR4 antagonism as a therapeutic approach to prevent acute kidney injury. Am J Phys. Renal Physiol 2014;307(7):F783–F797. DOI: 10.1152/ajprenal.00685.2013.
  36. Schrier RW, Wang W, Poole B, Mitra A. Acute renal failure: definitions, diagnosis, pathogenesis, and therapy. J Clin Invest 2004;114(1):5–14. DOI: 10.1172/JCI22353.
  37. Noiri E, Peresleni T, Miller F, Goligorsky MS. In vivo targeting of inducible NO synthase with oligodeoxynucleotides protects rat kidney against ischemia. J Clin Invest 1996;97(10):2377–2383. DOI: 10.1172/JCI118681.
  38. Kohjimoto Y, Kennington L, Scheid CR, Honeyman TW. Role of phospholipase A2 in the cytotoxic effects of oxalate in cultured renal epithelial cells. Kidney Int 1999;56(4):1432–1441. DOI: 10.1046/j.1523-1755.1999.00683.x.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.