Indian Journal of Critical Care Medicine

Register      Login



Volume / Issue

Online First

Related articles

VOLUME 24 , ISSUE 5 ( May, 2020 ) > List of Articles


Goal-directed Therapy: Does It Work in Postcardiac Surgery Patients, Unlike in Sepsis?

Sonali Saraf

Citation Information : Saraf S. Goal-directed Therapy: Does It Work in Postcardiac Surgery Patients, Unlike in Sepsis?. Indian J Crit Care Med 2020; 24 (5):287-288.

DOI: 10.5005/jp-journals-10071-23452

License: CC BY-NC 4.0

Published Online: 27-07-2020

Copyright Statement:  Copyright © 2020; The Author(s).


  1. Aya HD, Cecconi M, Hamilton M, Rhodes A. Goal-directed therapy in cardiac surgery: a systematic review and meta-analysis. Br J Anaesth 2013;110(4):510–517. DOI: 10.1093/bja/aet020.
  2. Rosner MH, Okusa MD. Acute kidney injury associated with cardiac surgery. Clin J Am Soc Nephrol 2006;1(1):19–32. DOI: 10.2215/CJN.00240605.
  3. Fergerson BD, Manecke Jr GR. Goal-directed therapy in cardiac surgery: are we there yet? J Cardiothorac Vasc Anesth 2013;27(6): 1075–1078. DOI: 10.1053/j.jvca.2013.08.004.
  4. Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, et al. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Intensive Care Med 2017;43(3):304–377. DOI: 10.1007/s00134-017-4683-6.
  5. Pearse RM, Harrison DA, MacDonald N, Gillies MA, Blunt M, Ackland G, et al. Effect of a perioperative, cardiac output-guided hemodynamic therapy algorithm on outcomes following major gastrointestinal surgery: a randomized clinical trial and systematic review. JAMA 2014;311(21):2181–2190. DOI: 10.1001/jama.2014.5305.
  6. Shoemaker WC, Appel PL, Kram HB, Waxman K, Lee TS. Prospective trial of supranormal values of survivors as therapeutic goals in high-risk surgical patients. Chest 1988;94(6):1176–1186. DOI: 10.1378/chest.94.6.1176.
  7. Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001;345(19):1368–1377. DOI: 10.1056/NEJMoa010307.
  8. Arulkumaran N, Corredor C, Hamilton MA, Ball J, Grounds RM, Rhodes A, et al. Cardiac complications associated with goal-directed therapy in high-risk surgical patients: a meta-analysis. Br J Anaesth 2014;112(4):648–659. DOI: 10.1093/bja/aet466.
  9. Osawa EA, Rhodes A, Landoni G, Galas FRBG, Fukushima JT, Park CHL, et al. Effect of perioperative goal-directed hemodynamic resuscitation therapy on outcomes following cardiac surgery: a randomized clinical trial and systematic review. Crit Care Med 2016;44(4):724–733. DOI: 10.1097/CCM.0000000000001479.
  10. O'Neal JB, Shaw AD. Goal-directed therapy in the operating room: is there any benefit? Curr Opin Anaesthesiol 2016;29(1):80–84. DOI: 10.1097/ACO.0000000000000273.
  11. Goldthwaite Z, Firstenberg MS, Botsch A. Hemodynamic early goal-directed therapy: explaining the fine print. Int J Crit Illn Inj Sci 2019;9(2):54–56. DOI: 10.4103/IJCIIS.IJCIIS_38_19.
  12. Patel H, Parikh N, Shah R, Patel R, Thosani R, Shah P, et al. Effect of goal-directed hemodynamic therapy in postcardiac surgery patients. Indian J Crit Care Med 2020;24(5):321–326.
  13. Engelman DT, Ben Ali W, Williams JB, Perrault LP, Seenu Reddy V, Arora RC, et al. Guidelines for perioperative care in cardiac surgery: enhanced recovery after surgery society recommendations. JAMA Surg 2019;154(8):755–766. DOI: 10.1001/jamasurg.2019. 1153.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.