Indian Journal of Critical Care Medicine

Register      Login

SEARCH WITHIN CONTENT

FIND ARTICLE

Volume / Issue

Online First

Archive
Related articles

VOLUME 25 , ISSUE 6 ( June, 2021 ) > List of Articles

EDITORIAL

Acute Respiratory Distress Syndrome in the Elderly

Citation Information : Acute Respiratory Distress Syndrome in the Elderly. Indian J Crit Care Med 2021; 25 (6):613-614.

DOI: 10.5005/jp-journals-10071-23877

License: CC BY-NC 4.0

Published Online: 01-06-2021

Copyright Statement:  Copyright © 2021; The Author(s).


Abstract

Acute respiratory distress syndrome (ARDS) is a commonly encountered complex syndrome of varied etiology and outcomes. The elderly population is at a high risk of developing severe ARDS with poor outcomes. The age-related changes in the immune system, structural and functional modifications of the respiratory system, and the frailty with a decrease in the physiological reserve of organ systems place them precariously for poor outcomes. However, does age alone influence the outcomes or is it the associated comorbidities that determine mortality in the elderly is not clearly known.


HTML PDF Share
  1. Schouten LRA, Bos LDJ, Serpa Neto A, van Vught LA, Wiewel MA, Hoogendijk AJ, et al. Increased mortality in elderly patients with acute respiratory distress syndrome is not explained by host response. Intensive Care Med Exp 2019;7:58. DOI: 10.1186/s40635-019-0270-1.
  2. Suchyta MR, Clemmer TP, Elliott CG, Orme JF, Morris AH, Jacobson J, et al. Increased mortality of older patients with acute respiratory distress syndrome. Chest 1997;111(5):1334–1339. DOI: 10.1378/chest.111.5.1334.
  3. Villar J, Ambrós A, Soler JA, Martínez D, Ferrando C, Solano R, et al. Age, PaO2/FIO2, and plateau pressure score. Crit Care Med 2016;44(7):1361–1369. DOI: 10.1097/CCM.0000000000001653.
  4. Song M, Liu Y, Lu Z, Luo H, Peng H, Chen P. Prognostic factors for ARDS: clinical, physiological and atypical immunodeficiency. BMC Pulm Med 2020;20(1):102. DOI: 10.1186/s12890-020-1131-0.
  5. Luo L, Shaver CM, Zhao Z, Koyama T, Calfee CS, Bastarache JA, et al. Clinical predictors of hospital mortality differ between direct and indirect ARDS. Chest 2017;151(4):755–763. DOI: 10.1016/j.chest.2016.09.004.
  6. Brody J, Thurlbeck W. Development, growth, and aging of the lung. In: Fishman A, Macklem P, Mead J, editors. Handbook of physiology, the respiratory system. Bethesda, Maryland: American Physiological Society; 1986. p. 355–386.
  7. Schouten LR, van Kaam AH, Kohse F, Veltkamp F, Bos LD, de Beer FM, et al. Age-dependent differences in pulmonary host responses in ARDS: a prospective observational cohort study. Ann Intensive Care 2019;9:55. DOI: 10.1186/s13613-019-0529-4.
  8. Sehgal IS, Agarwal R, Dhooria S, Prasad KT, Muthu V, Aggarwal AN. Etiology and Outcomes of ARDS in the Elderly Population in an Intensive Care Unit in North India. Indian J Crit Care Med 2021;25(6):648–654.
  9. Koutsoukou A, Katsiari M, Orfanos S, Rovina N, Dimitrakopoulou C, Kotanidou A, et al. ARDS in aged patients respiratory system mechanics and outcome. Health Sci J 2017;11:2. DOI: 10.21767/1791-809X.1000498.
  10. Herbert JA, Valentine MS, Saravanan N, Schneck MB, Pidaparti R, Fowler AA, et al. Conservative fluid management prevents age-associated ventilator induced mortality. Exp Gerontol 2016;81:101–109. DOI: 10.1016/j.exger.2016.05.005.
  11. Nadeem RN, Elhoufi AM, Soliman MA, Bon I, Obaida ZA, Hussien MM, et al. Clinical predictors of adherence to low tidal volume ventilation practice: is it different on weekend and night shifts? Cureus 2019;11(6):e4844. DOI: 10.7759/cureus.4844.
  12. Herridge MS, Tansey CM, Matte A, Tomlinson G, Diaz-Granados N, Cooper A, et al. Functional disability 5 years after acute respiratory distress syndrome. N Engl J Med 2011;364(14):1293–1304. DOI: 10.1056/NEJMoa1011802.
  13. Wilcox ME, Brummel NE, Archer K, Ely EW, Jackson JC, Hopkins RO. Cognitive dysfunction in ICU patients: risk factors, predictors, and rehabilitation interventions. Crit Care Med 2013;41(9 Suppl. 1):S81–S98. DOI: 10.1097/CCM.0b013e3182a16946.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.