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VOLUME 26 , ISSUE 6 ( June, 2022 ) > List of Articles


First Case of Acute Myocarditis Caused by Metapneumovirus in an Immunocompromised 14-year-old Girl

Anissa Makhlouf, Lise Peipoch, Pauline Duport, Etienne Darrieux, Yves Reguerre, Duksha Ramful, Jean-Luc Alessandri, Yael Levy

Keywords : Intravenous immunoglobulin, Leukemia, Metapneumovirus, Myocarditis, Venoarterial extracorporeal membrane oxygenation

Citation Information : Makhlouf A, Peipoch L, Duport P, Darrieux E, Reguerre Y, Ramful D, Alessandri J, Levy Y. First Case of Acute Myocarditis Caused by Metapneumovirus in an Immunocompromised 14-year-old Girl. Indian J Crit Care Med 2022; 26 (6):745-747.

DOI: 10.5005/jp-journals-10071-24255

License: CC BY-NC 4.0

Published Online: 20-06-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Background: Human metapneumovirus (hMPV) is a paramyxovirus, well known as a causative agent of respiratory tract infections. Non-respiratory manifestations, including cardiac impairments, remain rare. Only two cases of myocarditis caused by hMPV have been described in adults. Case description: We present the case of a 14-year-old female suffering from Burkitt leukemia and diagnosed with severe myocarditis caused by hMPV, based on results from real-time polymerase chain reaction (RT-PCR) and magnetic resonance imaging (MRI). She was successfully treated by venoarterial extracorporeal membrane oxygenation and intravenous immunoglobulins. She was discharged from pediatric intensive care unit (PICU) 3 weeks later. Conclusion: This is the first pediatric case of hMPV myocarditis requiring venoarterial extracorporeal membrane oxygenation.

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