Indian Journal of Critical Care Medicine

Register      Login



Volume / Issue

Online First

Related articles

VOLUME 26 , ISSUE 11 ( November, 2022 ) > List of Articles

Original Article

Six-month Morbidity and Mortality in Patients after Recovery from COVID-19

Keywords : Hospitalization, Mortality, Post-COVID-19, Symptoms

Citation Information : Six-month Morbidity and Mortality in Patients after Recovery from COVID-19. Indian J Crit Care Med 2022; 26 (11):1179-1183.

DOI: 10.5005/jp-journals-10071-24347

License: CC BY-NC 4.0

Published Online: 31-10-2022

Copyright Statement:  Copyright © 2022; The Author(s).


Background: This telephonic survey was aimed to identify the proportion of coronavirus disease-2019 (COVID-19) patients who died from any cause, within 6 months of discharge from a tertiary COVID-19 care hospital. We also analyzed whether any clinical and/or laboratory variables were associated with post-discharge mortality. Materials and methods: All adult patients (age ≥18 years) who had been discharged during the period between July 2020 and August 2020 from a tertiary COVID-19-care hospital after initial hospitalization for COVID-19 were included. A telephonic interview was conducted 6 months after discharge to assess morbidity and mortality in these patients. Results: Out of the 457 patients who responded, 79 patients (17.21%) were symptomatic, and breathlessness was found as most common symptom (6.12%). Fatigue was noted in (5.93%) of study patients, followed by cough (4.59%), sleep disturbances (4.37%), and headache (2.62%). Of the 457 patients who responded, 42 patients (9.19%) required expert medical consultation for their persistent symptoms. Thirty-six patients (7.88%) required re-hospitalization for post-COVID-19 complications within 6 months of discharge. A total of 10 patients (2.18%) succumbed within 6 months of their discharge from the hospital. 6 patients were males and 4 females. Most of these patients (7/10) succumbed in the second month after discharge. Seven patients had moderate-to-severe COVID-19 disease and most of these (7/10) had not been treated in the intensive care unit (ICU). Conclusion: Post-COVID-19 mortality figures were not very high in our survey despite the high perceived risk of thromboembolic events after recovery from COVID-19. A significant proportion of patients reported persistent post-COVID-19 symptoms. Breathing difficulty was the most common symptom noted by us, closely followed by fatigue.

PDF Share
  1. Carfì A, Bernabei R, Landi F. Persistent symptoms in patients after acute COVID-19. JAMA 2020;324(6):603–605. DOI: 10.1001/jama.2020.12603.
  2. Istituto Superiore Sanità. Sorveglianza Integrata COVID-19 in Italia. 2020. Available at: Accessed on: 8 March 2022.
  3. Somani SS, Richter F, Fuster V, de Freitas JK, Naik N, Sigel K, et al. Characterization of patients who return to hospital following discharge from hospitalization for COVID-19. J Gen Intern Med 2020;35(10):2838–2844. DOI: 10.1007/s11606-020-06120-6.
  4. Rokadiya S, Gil E, Stubbs C, Bell D, Herbert R. COVID-19: Outcomes of patients with confirmed COVID-19 re-admitted to hospital. J Infect 2020;81:e18–e19. DOI: 10.1016/j.jinf.2020.07.007.
  5. Zhou F, Yu T, Du R, Fan G, Liu Y, Xiang J, et al. Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: A retrospective cohort study. Lancet 2020;395:1054–1062. DOI: 10.1016/S0140-6736(20)30566-3.
  6. Rai DK, Sahay N, Lohani P. Clinical characteristics and treatment outcomes of 293 COVID-19 patients admitted to the intensive care unit of a tertiary care hospital of eastern India. Indian J Crit Care Med 2021;25(12):1395–1401. DOI: 10.5005/jp-journals-10071-24048.
  7. Aggarwal R, Bhatia R, Kulshrestha K, Soni KD, Viswanath R, Singh AK, et al. Clinicoepidemiological features and mortality analysis of deceased patients with COVID-19 in a tertiary care center. Indian J Crit Care Med 2021;25(6):622–628. DOI: 10.5005/jp-journals-10071-23848.
  8. Zhang P, Li J, Liu H, Han N, Ju J, Kou Y, et al. Long-term bone and lung consequences associated with hospital-acquired severe acute respiratory syndrome: A 15-year follow-up from a prospective cohort study. Bone Res 2020;8:8. DOI: 10.1038/s41413-020-0084-5.
  9. Huang C, Huang L, Wang Y, Li X, Ren L, Gu X, et al. 6-month consequences of COVID-19 in patients discharged from hospital: A cohort study. Lancet 2021;397(10270):220–232. DOI: 10.1016/S0140-6736(20)32656-8.
  10. Naik S, Haldar SN, Soneja M, Mundadan NG, Garg P, Mittal A, et al. Post-COVID-19 sequelae: A prospective observational study from Northern India. Drug Discov Ther 2021;15(5):254–260. DOI: 10.5582/ddt.2021.01093.
  11. Rai D, Sahay N, Pandey S. Morbidity among home isolated COVID-19 patients. J Assoc Physicians India 2021;69(2):77–78. PMID: 33527824.
  12. Donnelly JP, Wang XQ, Iwashyna TJ, Prescott HC. Readmission and death after initial hospital discharge among patients with COVID-19 in a large multihospital system. JAMA 2021;325(3):30306. DOI: 10.1001/jama.2020.21465. DOI: 10.1001/jama.2020.21465.
  13. Prakash A, Sahay N, Bhadani UK, Naaz S, Kumar R, Singh K, et al. COVID-19 lockdown and its impact on cancer pain management: A telephone survey of terminally ill patients. Palliat Med 2021; 35(6):1215–1217. DOI: 10.1177/02692163211011351.
PDF Share
PDF Share

© Jaypee Brothers Medical Publishers (P) LTD.