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VOLUME 26 , ISSUE 11 ( November, 2022 ) > List of Articles


Reckoning the Inhaled Sedation in Critically Ill Patients (INSTINCT) Study

Habib Md Reazaul Karim, Jayanta Kumar Mitra

Keywords : Age, Cost, Intensive care unit sedation, Volatile anesthetics

Citation Information : Karim HM, Mitra JK. Reckoning the Inhaled Sedation in Critically Ill Patients (INSTINCT) Study. Indian J Crit Care Med 2022; 26 (11):1227-1228.

DOI: 10.5005/jp-journals-10071-24356

License: CC BY-NC 4.0

Published Online: 31-10-2022

Copyright Statement:  Copyright © 2022; The Author(s).


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  1. Kulkarni AP, Bhosale SJ, Kalvin KR, Sahu TK, Mohanty R, Dhas MM, et al. INhaled SedaTion IN critically ill patients – (INSTINCT) study. Safety and feasibility of AnaConDa™ to deliver inhaled isoflurane for sedation in patients undergoing elective postoperative mechanical ventilation: A Prospective, Open-label, Interventional Trial (INSTINCT I Study). Indian J Crit Care Med 2022;26(8):906–912. DOI: 10.5005/jp-journals-10071-24264.
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  4. Long L, Ren S, Gong Y, Zhao H, He C, Shen L, et al. Different depths of sedation versus risk of delirium in adult mechanically ventilated patients: A systematic review and meta-analysis. PLoS One 2020; 15(7):e0236014. DOI: 10.1371/journal.pone.0236014.
  5. Gitti N, Renzi S, Marchesi M, Bertoni M, Lobo FA, Rasulo FA, et al. Seeking the light in intensive care unit sedation: the optimal sedation strategy for critically ill patients. Front Med 2022;9:901343. DOI: 10.3389/fmed.2022.901343.
  6. Karim HMR, Narayan A, Yunus M, Kumar S, Prakash A, Sahoo SK. An observational study on patient admission in the anaesthesia gas monitor and minimum alveolar concentration monitoring: A deficiency with huge impact. Indian J Anaesth 2017;61(7):570–574. DOI: 10.4103/ija.IJA_11_17.
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