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VOLUME 27 , ISSUE 2 ( February, 2023 ) > List of Articles


Blood Lactate in Early Sepsis: A Predictor to “Keep Up” Rather than “Catch Up”

Baby Sailaja

Keywords : Biomarker, Blood lactate, Early sepsis, Prognostic scoring models

Citation Information : Sailaja B. Blood Lactate in Early Sepsis: A Predictor to “Keep Up” Rather than “Catch Up”. Indian J Crit Care Med 2023; 27 (2):83-84.

DOI: 10.5005/jp-journals-10071-24406

License: CC BY-NC 4.0

Published Online: 31-01-2023

Copyright Statement:  Copyright © 2023; The Author(s).


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  1. Pregernig A, Müller M, Held U, Beck-Schimmer B. Prediction of mortality in adult patients with sepsis using six biomarkers: A systematic review and meta-analysis. Ann Intensive Care 2019;9(1):1–4. DOI: 10.1186/s13613-019-0600-1.
  2. Maitra S, Som A, Bhattacharjee S. Accuracy of quick Sequential Organ Failure Assessment (qSOFA) score and systemic inflammatory response syndrome (SIRS) criteria for predicting mortality in hospitalized patients with suspected infection: A meta-analysis of observational studies. Clin Microbiol Infect 2018;24(11):1123–1129. DOI: 10.1016/j.cmi.2018.03.032.
  3. Mikkelsen ME, Miltiades AN, Gaieski DF, Goyal M, Fuchs BD, Shah CV, et al. Serum lactate is associated with mortality in severe sepsis independent of organ failure and shock. Crit Care Med 2009;37(5):1670–1677. DOI: 10.1097/CCM.0b013e31819fcf68.
  4. Chaudhari M, Agarwal N. Study of significance of serum lactate kinetics in sepsis as mortality predictor. Indian J Crit Care Med 2022;26(5):591–595. DOI: 10.5005/jp-journals-10071-23935.
  5. Filho RR, Rocha LL, Corrêa TD, Pessoa CM, Colombo G, Assuncao MS. Blood lactate levels cutoff and mortality prediction in sepsis-time for a reappraisal? A retrospective cohort study. Shock 2016;46(5):480–485. DOI: 10.1097/SHK.0000000000000667.
  6. Vincent J-L, Quintairos E Silva A, Couto L Jr, Taccone FS. The value of blood lactate kinetics in critically ill patients: A systematic review. Crit Care 2016;20(1):257. DOI: 10.1186/s13054-016-1403-5.
  7. Levy B. Lactate and shock state: The metabolic view. Curr Opin Crit Care 12(4):315–321. DOI: 10.1097/01.ccx.0000235208.77450.15.
  8. Almutary A, Althunayyan S, Alenazi K, Alqahtani A, Alotaibi B, et al. National Early Warning Score (NEWS) as prognostic triage tool for septic patients. Infect Drug Resist 2020;13:3843–3851. DOI: 10.2147/IDR.S275390.
  9. Evans L, Rhodes A, Alhazzani W, Antonelli M, Coopersmith CM, French C, et al. Surviving sepsis campaign: International guidelines for management of sepsis and septic shock 2021. Crit Care Med 2021;49(11):e1063–e1143. DOI: 10.1097/CCM.0000000000005337.
  10. RCP. Royal College of Physicians. National early warning score (news) 2: Standardising the assessment of acute-illness severity in the NHS. Updated report of a working party. London: RCP.
  11. Noparatkailas N, Inchai J, Deesomchok A. Blood lactate level and the predictor of death in non-shock septic patients. Indian J Crit Care Med 2023;27(2):93–100.
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