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VOLUME 27 , ISSUE 4 ( April, 2023 ) > List of Articles


Optic Nerve Sheath Diameter and Sodium Levels: A Friend of a Friend is Still a Stranger

Keywords : Emergency department, Hyponatremia, Optic nerve sheath diameter, Osmotic demyelination syndrome, Raised intracranial pressure

Citation Information : Optic Nerve Sheath Diameter and Sodium Levels: A Friend of a Friend is Still a Stranger. Indian J Crit Care Med 2023; 27 (4):235-236.

DOI: 10.5005/jp-journals-10071-24444

License: CC BY-NC 4.0

Published Online: 31-03-2023

Copyright Statement:  Copyright © 2023; The Author(s).


  1. Uttanganakam S, Hansda U, Sahoo S, Shaji IM, Guru S, Topno N, et al. Sonographic optic nerve sheath diameter as a guide for correction of hyponatremia in the emergency department: A cross-sectional study. Indian J Crit Care Med 2023;27(4):265–269.
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  3. Chen LM, Wang LJ, Hu Y, Jiang XH, Wang YZ, Xing YQ. Ultrasonic measurement of optic nerve sheath diameter: A non-invasive surrogate approach for dynamic, real-time evaluation of intracranial pressure. Br J Ophthalmol 2019;103(4):437–441. DOI: 10.1136/bjophthalmol-2018-312934.
  4. Aletreby W, Alharthy A, Brindley PG, Kutsogiannis DJ, Faqihi F, Alzayer W, et al. Optic nerve sheath diameter ultrasound for raised intracranial pressure: A literature review and meta-analysis of its diagnostic accuracy. J Ultrasound Med 2022;41(3):585–595. DOI: 10.1002/jum.15732.
  5. Lochner P, Falla M, Brigo F, Pohl M, Strapazzon G. Ultrasonography of the optic nerve sheath diameter for diagnosis and monitoring of acute mountain sickness: A systematic review. High Alt Med Biol 2015;16(3):195–203. DOI: 10.1089/ham.2014.1127.
  6. Lee SH, Jong Yun S. Diagnostic performance of optic nerve sheath diameter for predicting neurologic outcome in post-cardiac arrest patients: A systematic review and meta-analysis. Resuscitation 2019;138:59–67. DOI: 10.1016/j.resuscitation.2019.03.004.
  7. Robba C, Santori G, Czosnyka M, Corradi F, Bragazzi N, Padayachy L, et al. Optic nerve sheath diameter measured sonographically as non-invasive estimator of intracranial pressure: A systematic review and meta-analysis. Intensive Care Med 2018;44(8):1284–1294. DOI: 10.1007/s00134-018-5305-7.
  8. Stevens RRF, Gommer ED, Aries MJH, Ertl M, Mess WH, Huberts W, et al. Optic nerve sheath diameter assessment by neurosonology: A review of methodologic discrepancies. J Neuroimaging 2021;31(5):814–825. DOI: 10.1111/jon.12906.
  9. Ohle R, McIsaac SM, Woo MY, Perry JJ. Sonography of the optic nerve sheath diameter for detection of raised intracranial pressure compared to computed tomography: A systematic review and meta-analysis. J Ultrasound Med 2015;34(7):1285–1294. DOI: 10.7863/ultra.34.7.1285.
  10. Spasovski G, Vanholder R, Allolio B, Annane D, Ball S, Bichet D, et al. Clinical practice guideline on diagnosis and treatment of hyponatraemia. Eur J Endocrinol 2014;170(3):G1–G47. DOI: 10.1530/EJE-13-1020.
  11. Lambeck J, Hieber M, Dreßing A, Niesen WD. Central pontine myelinosis and osmotic demyelination syndrome. Dtsch Ärztebl Int 2019;116(35–36):600–606. DOI: 10.3238/arztebl.2019.0600.
  12. Nicaise C, Marneffe C, Bouchat J, Gilloteaux J. Osmotic demyelination: From an oligodendrocyte to an astrocyte perspective. Int J Mol Sci 2019;20(5):1124. DOI: 10.3390/ijms20051124.
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