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VOLUME 27 , ISSUE 4 ( April, 2023 ) > List of Articles

Original Article

Frequency and Risk Factors of Hypophosphatemia in Patients Admitted to Emergency Intensive Care Unit in Zagazig University Hospitals

Ahmed El-Sayed Mohamed El-Sayed Bsar, Samia Abdel-Rahman El-Wakiel, Mona Abdel-Hameed El-Harrisi, Amr Shaaban Hafez Elshafei

Keywords : Accidental poisoning, Acute hypoxemic respiratory failure, Adolescent, Cardiac output blood pressure

Citation Information : Bsar AE, El-Wakiel SA, El-Harrisi MA, Elshafei AS. Frequency and Risk Factors of Hypophosphatemia in Patients Admitted to Emergency Intensive Care Unit in Zagazig University Hospitals. Indian J Crit Care Med 2023; 27 (4):277-282.

DOI: 10.5005/jp-journals-10071-24431

License: CC BY-NC 4.0

Published Online: 31-03-2023

Copyright Statement:  Copyright © 2023; The Author(s).


Background: Inorganic phosphate is a major electrolyte that participates in many functional and integral processes in the human body. Low Pi levels may lead to multiple organ dysfunction. It is estimated to occur in 40–80% of intensive care unit (ICU) patients. However, it may be ignored during the initial evaluation in ICU. Materials and methods: This prospective cross-sectional study included 500 adult ICU cases in two groups; a group with normal Pi levels and a group with hypophosphatemia. All admitted patients were subjected to full history taking, and clinical, laboratory, and radiological evaluation. Collected data were coded, processed, and analyzed using statistical package for social sciences (SPSS) software. Results: Among 500 adult ICU patients; 56.8% had normal phosphate levels while the remaining 43.2% had low phosphate levels. Patients in the hypophosphatemia group were associated with a significantly higher Acute Physiological and Chronic Health Evaluation (APACHE II) score, a longer hospital and ICU stay, a higher incidence of mechanical ventilation use with a longer duration on it, and a significantly higher mortality rate. Conclusion: Risk factors for hypophosphatemia include a higher APACHE II score, longer stay in the hospital and ICU, a higher ratio of mechanical ventilation, and a higher mortality rate.

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