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VOLUME 28 , ISSUE 1 ( January, 2024 ) > List of Articles

PEDIATRIC CRITICAL CARE MEDICINE

Incidence and Risk Factors of Acute Kidney Injury in Pediatric Liver Transplant Patients: A Retrospective Study

Duygu Demiroz, Yusuf Ziya Colak, Oya Olcay Ozdes, Muharrem Ucar, Mehmet Ali Erdogan, Hüseyin Ilksen Toprak, Serdar Karakas, Sevgi Demiroz Tasolar, Cemalettin Aydın, Ilknur Varol

Keywords : Acute kidney injury, Liver transplantation, Pediatric transplantation

Citation Information : Demiroz D, Colak YZ, Ozdes OO, Ucar M, Erdogan MA, Toprak HI, Karakas S, Tasolar SD, Aydın C, Varol I. Incidence and Risk Factors of Acute Kidney Injury in Pediatric Liver Transplant Patients: A Retrospective Study. Indian J Crit Care Med 2024; 28 (1):75-79.

DOI: 10.5005/jp-journals-10071-24616

License: CC BY-NC 4.0

Published Online: 30-12-2023

Copyright Statement:  Copyright © 2024; The Author(s).


Abstract

Background: Acute kidney injury (AKI) significantly contributes to the mortality and morbidity rates among pediatric liver transplant (LT) recipients. Objective: Our study aimed to assess the potential factors contributing to AKI in pediatric LT patients and to analyze the impact of AKI on postoperative mortality and hospitalization duration. Materials and methods: About 235 pediatric LT patients under the age of 18 between the years 2015 and 2021 were evaluated retrospectively. The relationship between preoperative and intraoperative variables of the patients and AKI developed when the early postoperatıve period was assessed. Results: A correlation was found between the patients’ preoperative age, albumin levels, and AKI. AKI was found to be associated with the duration of surgery and intraoperative blood transfusion. Conclusion: Our findings revealed that the severity of AKI in pediatric LT patients is linked to extended surgical durations and increased blood transfusions resulting from hemodynamically compromised blood loss. Furthermore, independent risk factors for AKI were identified as prolonged warm ischemia and the overall duration of the operation.

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