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VOLUME 28 , ISSUE 4 ( April, 2024 ) > List of Articles

BRIEF RESEARCH COMMUNICATION

A Retrospective Study on UTI by Myroides Species: An Emerging Drug Resistant Nosocomial Pathogen

Chinmoy Sahu, Radhika Chaudhary, Chitra Bhartiya, Sangram S Patel, Nidhi Bhatnagar

Keywords : Multidrug resistance, Myroides species, Nosocomial infection, Urinary tract infection

Citation Information : Sahu C, Chaudhary R, Bhartiya C, Patel SS, Bhatnagar N. A Retrospective Study on UTI by Myroides Species: An Emerging Drug Resistant Nosocomial Pathogen. Indian J Crit Care Med 2024; 28 (4):399-403.

DOI: 10.5005/jp-journals-10071-24683

License: CC BY-NC 4.0

Published Online: 30-03-2024

Copyright Statement:  Copyright © 2024; The Author(s).


Abstract

Aim and background: Myroides (M.) species are ubiquitous in the environment and cause a variety of infections like urinary tract infections (UTI), sepsis, meningitis, cholecystitis, pneumonia, and soft tissue infections, especially among immunocompromised populations. These are usually resistant to multiple antibiotics. This study aimed to demonstrate the clinical profile, underlying comorbidities, and antimicrobial susceptibility of Myroides isolates obtained from nosocomial UTI cases. Materials and methods: A sudden rise in the isolation of Myroides spp. from the repeated urine samples of admitted patients alerted us to conduct this retrospective observational study. Urine cultures that grew M. species were included in this study. Antibiotic susceptibility was performed and the patient's clinical data was analyzed. Results: A total of 14 Myroides spp. isolates were obtained from urine culture. The maximum number of cases (71.4%) were from the Nephrology ward and ICUs. The average (mean) age of patients was 46 years (range 2–80 years). All patients were catheterized. All isolates were multidrug resistant. Minocycline and doxycycline were the only drugs found effective in this study. Conclusions: Myroides species are emerging rare pathogens that can cause UTI in immunocompromised and catheterized patients. Minocycline may be used for treating such infections.


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  1. Khan HA, Baig F K, Mehboob R. Nosocomial infections: Epidemiology, prevention, control and surveillance. Asian Pac J Trop Biomed 2017;7(5):478–482. DOI: https://doi.org/10.1016/j.apjtb.2017.01.019.
  2. Vancanneyt M, Segers P, Torck U, Hoste B, Bernardet JF, Vandamme P, et al. Reclassification of flavobacterium odoratum (Stutzer 1929) strains to a new genus, myroides, as myroides odoratus comb. nov. and myroides odoratimimus sp. nov. International Journal of Systematic and Evolutionary Microbiology 1996;46(4):926–932. DOI: http://dx.doi.org/10.1099/00207713-46-4-926.
  3. Beharrysingh R. Myroides bacteremia: A case report and concise review. IDCases 2017;8:34–36. DOI: 10.1016/j.idcr.2017.02.012.
  4. Mahendran AJ, Agrawal S, Rastogi N, Gupta N. Myroides: A rare but hard-to-crack villain in a critical care setup. Indian J Crit Care Med 2021;25(6):735–736. DOI: 10.5005/jp-journals-10071-23845.
  5. Parida S, Mishra SK. Urinary tract infections in the critical care unit: A brief review. Indian J Crit Care Med 2013;17(6):370–374. DOI: 10.4103/0972-5229.123451.
  6. Stamm WE, Norrby SR. Urinary tract infections: Disease panorama and challenges. J Infect Disease 2001;183(Supplement_1):S1–S4. DOI: 10.1086/318850.
  7. Holmes B, Snell JJ, Lapage SP. Flavobacterium odoratum: A species resistant to a wide range of antimicrobial agents. J Clin Pathol 1979;32(1):73–77. DOI: 10.1136/jcp.32.1.73.
  8. Deepa R, Venkatesh KG, Parveen JD, Banu ST, Jayalakshmi G. Myroides odoratus and Chryseobacterium indologenes: Two rare isolates in the immunocompromised. Indian J Med Microbiol 2014;32(3):327–330. DOI: 10.4103/0255-0857.136592.
  9. Thomas M, Padmini SB, Govindan VK, Appalaraju B. Oerskovia turbata and myroides species: Rare isolates from a case of acalculus cholecystitis. Indian J Med Microbiol 2007;25(3):297–298. DOI: 10.4103/0255-0857.34782.
  10. Agrawal M, Mamoria VP, Mittal S, Sharma A. Myroides: An emerging pathogen causing urinary tract infections in hospitalized patients. International Journal of Contemporary Medical Research 2019;6(11):K11–K14. DOI: http://dx.doi.org/10.21276/ijcmr.2019. 6.11.28.
  11. Verma Y, Hemachander SS, Shah K. Urinary tract infection caused by Myroides spp. In diabetic patients: To be or not to be. Indian J Case Reports 2018;4(1):1–3. DOI: 10.7860/JCDR/2020/46584.14322.
  12. Khan U, Pandey E, Gandham N, Das N, Mukhida S, Kannuri S, et al. A case series and literature review of infections due to Myroides spp: Identification of contributing factors and emerging antibiotic susceptibility trends. Access Microbiol 2023;5(5):acmi000549.v2. DOI: 10.1099/acmi.0.000549.v2.
  13. Pompilio A, Galardi G, Verginelli F, Muzzi M, Di Giulio A, Di Bonaventura G. Myroides odoratimimus forms structurally complex and inherently antibiotic-resistant biofilm in a wound-like in vitro model. Front Microbiol 2017;8:2591. DOI: 10.3389/fmicb.2017.02591.
  14. Hu SH, Yuan SX, Qu H, Jiang T, Zhou YJ, Wang MX, et al. Antibiotic resistance mechanisms of Myroides sp. J Zhejiang Univ Sci B 2016;17(3):188–199. DOI: 10.1631/jzus.B1500068.
  15. Licker M, Sorescu T, Rus M, Cirlea N, Horhat F, Jurescu C, et al. Extensively drug-resistant Myroides odoratimimus–A case series of urinary tract infections in immunocompromised patients. Infect Drug Resist 2018;11:743–749. DOI: 10.2147/IDR.S161069.
  16. Taşkın Kafa AH, Hasbek M. Synergistic efficacy of meropenem, ciprofloxacin and colistin antibiotics against planktonic and biofilm forms of Myroides odoratimimus bacterial isolates. Indian J Med Microbiol 2022;40(3):399–403. DOI: https://doi.org/10.1016/j.ijmmb.2022.04.004.
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