The HScore to Diagnose HLH in Scrub Typhus: Overdiagnosis or under Diagnosis and Does It Really Matter?

doi:10.5005/jp-journals-10071-24802

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The HScore to Diagnose HLH in Scrub Typhus: Overdiagnosis or under Diagnosis and Does It Really Matter?

Keywords : Scrub typhus and hemophagocytic lymphohistiocytosis, Secondary hemophagocytic lymphohistiocytosis, Tropical infections and hemophagocytic lymphohistiocytosis

Citation Information : The HScore to Diagnose HLH in Scrub Typhus: Overdiagnosis or under Diagnosis and Does It Really Matter?. Indian J Crit Care Med 2024; 28 (9):811-812.

DOI: 10.5005/jp-journals-10071-24802

License: CC BY-NC 4.0

Published Online: 31-08-2024

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Farquhar JW, Claireaux AE. Familial haemophagocytic reticulosis. Arch Dis Child 1952;27(136):519–525. DOI: 10.1136/adc.27.136.519.
Lachmann G, La Rosee P, Schenk T, Brunkhorst FM, Spies C. Hemophagocytic lymphohistiocytosis: A diagnostic challenge on the ICU. Anaesthesist 2016;65(10):776–786. DOI: 10.1007/s00101-016-0216-x.
Canna SW, Behrens EM. Making sense of the cytokine storm: A conceptual framework for understanding, diagnosing, and treating hemophagocytic syndromes. Pediatr Clin North Am 2012;59(2):329–344. DOI: 10.1016/j.pcl.2012.03.002.
Rajagopala S, Singh N. Diagnosing and treating hemophagocytic lymphohistiocytosis in the tropics: Systematic review from the Indian subcontinent. Acta Med Acad 2012;41(2):161–174. DOI: 10.5644/ama2006-124.49.
Kodan P, Chakrapani M, Shetty M, Pavan R, Bhat P. Hemophagocytic lymphohistiocytosis secondary to infections: A tropical experience! J Postgrad Med 2015;61(2):112–115. DOI: 10.4103/0022-3859.150904.
Selvam S, Tuli A, Yuvasai KP, Saini S, Erla SR, Kaur J, et al. Predicting secondary hemophagocytic lymphohistiocytosis in adult patients with scrub typhus and its prognostic significance. Indian J Crit Care Med 2024;28(9):823–831.
Henter JI, Horne AC, Aricó M, Egeler RM, Filipovich AH, Imashuku S, et al. HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer 2007;48(2):124–131. DOI: 10.1002/pbc.21039.
Fardet L, Galicier L, Lambotte O, Marzac C, Aumont C, Chahwan D, et al. Development and validation of the HScore, a score for the diagnosis of reactive Hemophagocytic syndrome. Arthritis Rheumatol 2014;66(9):2613–2620. DOI: 10.1002/art.38690.
Knaak C, Nyvlt P, Schuster FS, Spies C, Heeren P, Schenk T, et al. Hemophagocytic lymphohistiocytosis in critically ill patients: diagnostic reliability of HLH-2004 criteria and HScore. Crit Care 2020;24;24(1):244. DOI: 10.1186/s13054-020-02941-3.
Meena NK, Sinokrot O, Duggal A, Alpat D, Singh ZN, Coviello JM, et al. The performance of diagnostic criteria for hemophagocytic lymphohistiocytosis in critically ill patients. J Intensive Care Med 2020;35(12):1476–1482. DOI: 10.1177/0885066619837139.
Kan FK, Tan CC, Von Bahr Greenwood T, Khalid KE, Supramaniam P, Hed Myrberg I, et al. Dengue infection complicated by hemophagocytic lymphohistiocytosis: Experiences from 180 patients with severe dengue. Clin Infect Dis 2020;70(11):2247–2255. DOI: 10.1093/cid/ciz499.

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